Continuously rising trends in obesity-related malignancies render this disease spectrum a
public health priority. Worldwide, the burden of cancer attributable to obesity, expressed as …

Adipose tissue in addition to its ability to keep lipids is now recognized as a real organ with
both metabolic and endocrine functions. Recent studies demonstrated that in obese animals …

Obesity-related breast cancer is an important threat that affects especially post-menopausal
women. The link between obesity and breast cancer seems to be relying on the …

Background Breast cancer (BC) is the second most frequent type of cancer in the world and
most common among women, configuring a major challenge to global health. BC is a …

Several studies show that a significantly stronger association is obvious between increased
body mass index (BMI) and higher breast cancer incidence. Furthermore, obese women are …

Anti–vascular endothelial growth factor (VEGF) therapy has failed to improve survival in
patients with breast cancer (BC). Potential mechanisms of resistance to anti-VEGF therapy …

Background Adiponectin, the most abundant adipokine derived from adipose tissue, exhibits
a potent suppressive effect on the growth of breast cancer cells; however, the underlying …

Metabolic syndrome is a type of multifactorial metabolic disease with the presence of at least
three factors: obesity, diabetes mellitus, low high-density lipoprotein, hypertriglyceridemia …

Tumor‐associated macrophages (TAMs) are the most abundant inflammatory cells and
orchestrate different stages of breast cancer development. TAMs participate in the tumor …

Obesity, defined as the abnormal or excessive expansion of white adipose tissue, has
reached pandemic proportions and is recognized as an important health concern since it is …