Mechanistic evaluations of processes that underlie organism-level physiology often require
reductionist approaches. Dermal fibroblasts offer one such approach. These cells are easily …

Simple Summary It is paramount to preserve the genetic material of endangered wildlife
species for future generations, including that of the African savanna elephant (Loxodonta …

The risk of develo** cancer is correlated with body size and lifespan within species, but
there is no correlation between cancer and either body size or lifespan between species …

The enhanced availability of functional fibroblasts from precious tissue samples requires an
ideal cell-culture system. Therefore, this study was designed to investigate the performance …

The establishment of fibroblast lines enables several applications from the formation of
biobanks for the conservation of biodiversity to the use of these cells in physiological and …

Among the constraints on the evolution of remarkably long lifespans is an increased risk of
develo** cancer because organisms with long lifespans have more time to accumulate …

Owing to the inherent heterogeneity and plasticity of fibroblasts, they are considered as the
conventional biological resources for basic and clinical medical research. Thus, it is …

Following population declines of the African savanna elephant (Loxodonta africana) across
the African continent, the establishment of primary cell lines of this endangered wildlife …

Logic would suggest that cancer incidence is related to body mass and longevity. Gigantic
animals such as elephants with a longer lifespan (more lifetime of cell divisions) and a larger …

Owing to the inherent heterogeneity and plasticity of fibroblasts, they are considered as the
conventional biological resources for basic and clinical medical research. Thus, it is …