The essential medicinal chemistry of curcumin: miniperspective
Curcumin is a constituent (up to∼ 5%) of the traditional medicine known as turmeric. Interest
in the therapeutic use of turmeric and the relative ease of isolation of curcuminoids has led …
in the therapeutic use of turmeric and the relative ease of isolation of curcuminoids has led …
Targeting epigenetic regulators for cancer therapy: mechanisms and advances in clinical trials
Y Cheng, C He, M Wang, X Ma, F Mo, S Yang… - Signal transduction and …, 2019 - nature.com
Epigenetic alternations concern heritable yet reversible changes in histone or DNA
modifications that regulate gene activity beyond the underlying sequence. Epigenetic …
modifications that regulate gene activity beyond the underlying sequence. Epigenetic …
[HTML][HTML] Impacts of turmeric and its principal bioactive curcumin on human health: Pharmaceutical, medicinal, and food applications: A comprehensive review
The yellow polyphenolic pigment known as curcumin, originating from the rhizome of the
turmeric plant Curcuma longa L., has been utilized for ages in ancient medicine, as well as …
turmeric plant Curcuma longa L., has been utilized for ages in ancient medicine, as well as …
A review on antibacterial, antiviral, and antifungal activity of curcumin
S Zorofchian Moghadamtousi… - BioMed research …, 2014 - Wiley Online Library
Curcuma longa L.(Zingiberaceae family) and its polyphenolic compound curcumin have
been subjected to a variety of antimicrobial investigations due to extensive traditional uses …
been subjected to a variety of antimicrobial investigations due to extensive traditional uses …
Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic …
BB Aggarwal, KB Harikumar - The international journal of biochemistry & …, 2009 - Elsevier
Although safe in most cases, ancient treatments are ignored because neither their active
component nor their molecular targets are well defined. This is not the case, however, with …
component nor their molecular targets are well defined. This is not the case, however, with …
Cancer epigenetics reaches mainstream oncology
M Rodríguez-Paredes, M Esteller - Nature medicine, 2011 - nature.com
Epigenetics is one of the most promising and expanding fields in the current biomedical
research landscape. Since the inception of epigenetics in the 1940s, the discoveries …
research landscape. Since the inception of epigenetics in the 1940s, the discoveries …
Curcumin—from molecule to biological function
T Esatbeyoglu, P Huebbe, IMA Ernst… - Angewandte Chemie …, 2012 - Wiley Online Library
Turmeric is traditionally used as a spice and coloring in foods. It is an important ingredient in
curry and gives curry powder its characteristic yellow color. As a consequence of its intense …
curry and gives curry powder its characteristic yellow color. As a consequence of its intense …
Cellular and molecular mechanisms of curcumin in prevention and treatment of disease
Curcumin is a naturally occurring polyphenolic compound present in rhizome of Curcuma
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …
Anti-infective properties of the golden spice curcumin
D Praditya, L Kirchhoff, J Brüning… - Frontiers in …, 2019 - frontiersin.org
The search for novel anti-infectives is one of the most important challenges in natural
product research, as diseases caused by bacteria, viruses, and fungi are influencing the …
product research, as diseases caused by bacteria, viruses, and fungi are influencing the …
Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets
BB Aggarwal, B Sung - Trends in pharmacological sciences, 2009 - cell.com
Curcumin (diferuloylmethane), a yellow pigment in the spice turmeric (also called curry
powder), has been used for centuries as a treatment for inflammatory diseases. Extensive …
powder), has been used for centuries as a treatment for inflammatory diseases. Extensive …