The essential medicinal chemistry of curcumin: miniperspective

KM Nelson, JL Dahlin, J Bisson, J Graham… - Journal of medicinal …, 2017 - ACS Publications
Curcumin is a constituent (up to∼ 5%) of the traditional medicine known as turmeric. Interest
in the therapeutic use of turmeric and the relative ease of isolation of curcuminoids has led …

Targeting epigenetic regulators for cancer therapy: mechanisms and advances in clinical trials

Y Cheng, C He, M Wang, X Ma, F Mo, S Yang… - Signal transduction and …, 2019 - nature.com
Epigenetic alternations concern heritable yet reversible changes in histone or DNA
modifications that regulate gene activity beyond the underlying sequence. Epigenetic …

[HTML][HTML] Impacts of turmeric and its principal bioactive curcumin on human health: Pharmaceutical, medicinal, and food applications: A comprehensive review

MT El-Saadony, T Yang, SA Korma, M Sitohy… - Frontiers in …, 2023 - frontiersin.org
The yellow polyphenolic pigment known as curcumin, originating from the rhizome of the
turmeric plant Curcuma longa L., has been utilized for ages in ancient medicine, as well as …

A review on antibacterial, antiviral, and antifungal activity of curcumin

S Zorofchian Moghadamtousi… - BioMed research …, 2014 - Wiley Online Library
Curcuma longa L.(Zingiberaceae family) and its polyphenolic compound curcumin have
been subjected to a variety of antimicrobial investigations due to extensive traditional uses …

Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic …

BB Aggarwal, KB Harikumar - The international journal of biochemistry & …, 2009 - Elsevier
Although safe in most cases, ancient treatments are ignored because neither their active
component nor their molecular targets are well defined. This is not the case, however, with …

Cancer epigenetics reaches mainstream oncology

M Rodríguez-Paredes, M Esteller - Nature medicine, 2011 - nature.com
Epigenetics is one of the most promising and expanding fields in the current biomedical
research landscape. Since the inception of epigenetics in the 1940s, the discoveries …

Curcumin—from molecule to biological function

T Esatbeyoglu, P Huebbe, IMA Ernst… - Angewandte Chemie …, 2012 - Wiley Online Library
Turmeric is traditionally used as a spice and coloring in foods. It is an important ingredient in
curry and gives curry powder its characteristic yellow color. As a consequence of its intense …

Cellular and molecular mechanisms of curcumin in prevention and treatment of disease

SS Patel, A Acharya, RS Ray, R Agrawal… - Critical reviews in …, 2020 - Taylor & Francis
Curcumin is a naturally occurring polyphenolic compound present in rhizome of Curcuma
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …

Anti-infective properties of the golden spice curcumin

D Praditya, L Kirchhoff, J Brüning… - Frontiers in …, 2019 - frontiersin.org
The search for novel anti-infectives is one of the most important challenges in natural
product research, as diseases caused by bacteria, viruses, and fungi are influencing the …

Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets

BB Aggarwal, B Sung - Trends in pharmacological sciences, 2009 - cell.com
Curcumin (diferuloylmethane), a yellow pigment in the spice turmeric (also called curry
powder), has been used for centuries as a treatment for inflammatory diseases. Extensive …