Atypical antipsychotics: mechanism of action

P Seeman - The Canadian Journal of Psychiatry, 2002 - journals.sagepub.com
Background: Al though the prin ci pal brain tar get that all an tipsy chotic drugs at tach to is
the do pamine D2 re cep tor, tra di tional or typi cal an tipsy chot ics, by at tach ing to it, in …

Dopamine receptors and brain function

M Jaber, SW Robinson, C Missale, MG Caron - Neuropharmacology, 1996 - Elsevier
In the central nervous system (CNS), dopamine is involved in the control of locomotion,
cognition, affect and neuroendocrine secretion. These actions of dopamine are mediated by …

[КНИГА][B] Affect regulation and the origin of the self: The neurobiology of emotional development

AN Schore - 2015 - taylorfrancis.com
For over three decades, Allan N. Schore has authored numerous volumes, chapters, and
articles on regulation theory, a biopsychosocial model of the development …

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

HHM Van Tol, JR Bunzow, HC Guan, RK Sunahara… - Nature, 1991 - nature.com
DOPAMINE receptors belong to the family of G protein-coupled receptors. On the basis of
the homology between these receptors, three different dopamine receptors (D1, D2, D3) …

Dopaminergic modulation of neuronal excitability in the striatum and nucleus accumbens

SM Nicola, DJ Surmeier… - Annual review of …, 2000 - annualreviews.org
The striatum and its ventral extension, the nucleus accumbens, are involved in behaviors as
diverse as motor planning, drug seeking, and learning. Invariably, these striatally mediated …

Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1

RK Sunahara, HC Guan, BF O'Dowd, P Seeman… - Nature, 1991 - nature.com
DOPAMINE receptors belong to a superfamily of receptors that exert their biological effects
through guanine nucleotide-binding (G) proteins. Two main dopamine receptor subtypes …

Molecular biology of dopamine receptors

DR Sibley, FJ Monsma Jr - Trends in pharmacological sciences, 1992 - Elsevier
The application of modem molecular biological methods has had an increasing and
dramatic impact upon the discipline of molecular neuropharmacology. This is particularly …

Localization of dopamine D3 receptor mRNA in the rat brain using in situ hybridization histochemistry: comparison with dopamine D2 receptor mRNA

ML Bouthenet, E Souil, MP Martres, P Sokoloff, B Giros… - Brain research, 1991 - Elsevier
The messenger RNA (mRNA) of the recently characterized D 3 dopamine receptor was
visualized on rat brain sections using in situ hybridization with a 32 P-labeled ribonucleic …

Localization of D1 and D2 dopamine receptors in brain with subtype-specific antibodies.

AI Levey, SM Hersch, DB Rye, RK Sunahara… - Proceedings of the …, 1993 - pnas.org
Five or more dopamine receptor genes are expressed in brain. However, the
pharmacological similarities of the encoded D1-D5 receptors have hindered studies of the …

Allelic association of the D2 dopamine receptor gene with receptor-binding characteristics in alcoholism or gene ism

EP Noble, K Blum, T Ritchie… - Archives of general …, 1991 - jamanetwork.com
• The allelic association of the human D 2 dopamine receptor gene with the binding
characteristics of the D 2 dopamine receptor was determined in 66 brains of alcoholic and …