Sepsis-associated acute kidney injury (S-AKI) is a frequent complication of the critically ill
patient and is associated with unacceptable morbidity and mortality. Prevention of S-AKI is …

Sepsis is defined as organ dysfunction resulting from the host's deleterious response to
infection. One of the most common organs affected is the kidneys, resulting in sepsis …

Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …

Objective To provide an update to “Surviving Sepsis Campaign Guidelines for Management
of Sepsis and Septic Shock: 2012”. Design A consensus committee of 55 international …

Background Both balanced crystalloids and saline are used for intravenous fluid
administration in critically ill adults, but it is not known which results in better clinical …

Background Whether the use of balanced multielectrolyte solution (BMES) in preference to
0.9% sodium chloride solution (saline) in critically ill patients reduces the risk of acute kidney …

Importance Intravenous fluids are used for almost all intensive care unit (ICU) patients.
Clinical and laboratory studies have questioned whether specific fluid types result in …

Background Comparative clinical effects of balanced crystalloids and saline are uncertain,
particularly in noncritically ill patients cared for outside an intensive care unit (ICU). Methods …

Acute kidney injury (AKI) and sepsis carry consensus definitions. The simultaneous
presence of both identifies septic AKI. Septic AKI is the most common AKI syndrome in ICU …

Cardiac surgery-associated acute kidney injury (CSA-AKI) is the most common clinically
important complication in adult patients undergoing open heart surgery, and is associated …