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[HTML][HTML] The pharmacological properties of red grape polyphenol resveratrol: Clinical trials and obstacles in drug development
M Farhan, A Rizvi - Nutrients, 2023 - mdpi.com
Resveratrol is a stilbenoid from red grapes that possesses a strong antioxidant activity.
Resveratrol has been shown to have anticancer activity, making it a promising drug for the …
Resveratrol has been shown to have anticancer activity, making it a promising drug for the …
Nano-delivery systems for food bioactive compounds in cancer: Prevention, therapy, and clinical applications
Bioactive compounds represent a broad class of dietary metabolites derived from fruits and
vegetables, such as polyphenols, carotenoids and glucosinolates with potential for cancer …
vegetables, such as polyphenols, carotenoids and glucosinolates with potential for cancer …
[HTML][HTML] Combination therapy using polyphenols: An efficient way to improve antitumoral activity and reduce resistance
Polyphenols represent a structural class of mainly natural organic chemicals that contain
multiple phenol structural units. The beneficial properties of polyphenols have been …
multiple phenol structural units. The beneficial properties of polyphenols have been …
[HTML][HTML] Intranasal administration of edaravone nanoparticles improves its stability and brain bioavailability
Y Lu, JTW Wang, N Li, X Zhu, Y Li, S Bansal… - Journal of Controlled …, 2023 - Elsevier
The clinical application of EDV, a potent antioxidant drug approved for amyotrophic lateral
sclerosis (ALS), is limited by its short biological half-life and poor water solubility …
sclerosis (ALS), is limited by its short biological half-life and poor water solubility …
Zein nanoparticles as low-cost, safe, and effective carriers to improve the oral bioavailability of resveratrol
The clinical translation of the multiple pharmacological effects of resveratrol (RSV) found in
preclinical studies has been impaired by its poor bioavailability, due to poor solubility and …
preclinical studies has been impaired by its poor bioavailability, due to poor solubility and …
[HTML][HTML] Nano-strategies targeting the integrin αvβ3 network for cancer therapy
Integrin αvβ3, a cell surface receptor, participates in signaling transduction pathways in
cancer cell proliferation and metastasis. Several ligands bind to integrin αvβ3 to regulate …
cancer cell proliferation and metastasis. Several ligands bind to integrin αvβ3 to regulate …
Research progress on nanotechnology for delivery of active ingredients from traditional Chinese medicines
L Qiao, M Han, S Gao, X Shao, X Wang… - Journal of Materials …, 2020 - pubs.rsc.org
There is growing acceptance of traditional Chinese medicines (TCMs) as potential sources
of clinical agents based on the demonstrated efficacies of numerous bioactive compounds …
of clinical agents based on the demonstrated efficacies of numerous bioactive compounds …
Resveratrol's anti-cancer effects through the modulation of tumor glucose metabolism
Simple Summary The prevention and treatment of cancer is an ongoing medical challenge.
In the context of personalized medicine, the well-studied polyphenol resveratrol could …
In the context of personalized medicine, the well-studied polyphenol resveratrol could …
Third-generation solid dispersion combining Soluplus and poloxamer 407 enhances the oral bioavailability of resveratrol
Resveratrol is a very promising anti-oxidant drug candidate with low oral bioavailability due
to its intrinsic poor water solubility, intestinal efflux and metabolization mechanisms …
to its intrinsic poor water solubility, intestinal efflux and metabolization mechanisms …
Inulin-pluronic-stearic acid based double folded nanomicelles for pH-responsive delivery of resveratrol
Herein, we introduce a novel amphiphilic bioconjugate (INU-F68-SA), synthesized by
functionalization of pluronic F68 with a polysaccharide inulin (INU) and a lipid stearic acid …
functionalization of pluronic F68 with a polysaccharide inulin (INU) and a lipid stearic acid …