Purpose. NSAIDs constitute an important class of drugs with therapeutic applications that
have spanned several centuries. Treatment of inflammatory conditions such as rheumatoid …

Drug design in recent years has attempted to explore new chemical spaces resulting in
more complex, larger molecular weight molecules, often with limited water solubility. To …

Pyrazoles are of considerable interest due to the broad variety of their biological activities.
This overview summarizes structures of pharmacologically interesting pyrazoles, natural …

In the recent past trifluoromethylpyrazoles have gained much attention, particularly as anti-
inflammatory and antibacterial agents, in the field of medicinal chemistry. The location of …

炎症引发的疾病是人类常见的免疫系统疾病, 医药市场对抗炎药物的需求量极大.
花生四烯酸代谢网络是产生炎症介质的主要网络, 网络中的一些蛋白质已成为抗炎药物设计的 …

This is a review of classical and novel concepts of drug delivery in particular diseases such
as central nervous system disease, ophthalmic disease, cardiovascular disease, cancer and …