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Oxidative stress and redox-modulating therapeutics in inflammatory bowel disease
Inflammatory bowel disease (IBD) is associated with the production of reactive species that
target cysteine redox switches in proteins, thereby affecting gene regulation, DNA damage …
target cysteine redox switches in proteins, thereby affecting gene regulation, DNA damage …
Overview of cytokines and nitric oxide involvement in immuno-pathogenesis of inflammatory bowel diseases
Inflammatory bowel diseases (IBDs), including Crohn's disease and ulcerative colitis are
complex disorders with undetermined etiology. Several hypotheses suggest that IBDs result …
complex disorders with undetermined etiology. Several hypotheses suggest that IBDs result …
Renal damage induced by cadmium and its possible therapy by mitochondrial transplantation
EY Hernández-Cruz, I Amador-Martínez… - Chemico-Biological …, 2022 - Elsevier
Cadmium (Cd) is one of the most toxic metals without biological function, and its
accumulation in living organisms has been reported. The kidney is a target organ in Cd …
accumulation in living organisms has been reported. The kidney is a target organ in Cd …
Nitric oxide and peroxynitrite in health and disease
P Pacher, JS Beckman, L Liaudet - Physiological reviews, 2007 - journals.physiology.org
The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …
Protein carbonyl groups as biomarkers of oxidative stress
Oxidative stress, an imbalance toward the pro-oxidant side of the pro-oxidant/antioxidant
homeostasis, occurs in several human diseases. Among these diseases are those in which …
homeostasis, occurs in several human diseases. Among these diseases are those in which …
Tannic acid and zinc ion coordination of nanase for the treatment of inflammatory bowel disease by promoting mucosal repair and removing reactive oxygen and …
C Zhang, Q Li, J **ng, Y Yang, M Zhu, L Lin, Y Yu… - Acta Biomaterialia, 2024 - Elsevier
Colon mucosal overexpression of reactive oxygen and nitrogen species (RONS) accelerates
the development of inflammatory bowel disease (IBD) and destroys the mucosa and its …
the development of inflammatory bowel disease (IBD) and destroys the mucosa and its …
The role of oxidative stress in pathogenesis and treatment of inflammatory bowel diseases
A Piechota-Polanczyk, J Fichna - Naunyn-Schmiedeberg's archives of …, 2014 - Springer
In this review, we focus on the role of oxidative stress in the aetiology of inflammatory bowel
diseases (IBD) and colitis-associated colorectal cancer and discuss free radicals and free …
diseases (IBD) and colitis-associated colorectal cancer and discuss free radicals and free …
Endothelial mitochondrial oxidative stress determines podocyte depletion in segmental glomerulosclerosis
I Daehn, G Casalena, T Zhang, S Shi… - The Journal of clinical …, 2014 - jci.org
Focal segmental glomerular sclerosis (FSGS) is a primary kidney disease that is commonly
associated with proteinuria and progressive loss of glomerular function, leading to …
associated with proteinuria and progressive loss of glomerular function, leading to …
Effects of amino acid-derived luminal metabolites on the colonic epithelium and physiopathological consequences
Depending on the amount of alimentary proteins, between 6 and 18 g nitrogenous material
per day enter the large intestine lumen through the ileocaecal junction. This material is used …
per day enter the large intestine lumen through the ileocaecal junction. This material is used …
Ursolic acid: An anti‐and pro‐inflammatory triterpenoid
Y Ikeda, A Murakami, H Ohigashi - Molecular nutrition & food …, 2008 - Wiley Online Library
There is growing interest in the elucidation of the biological functions of triterpenoids,
ubiquitously distributed throughout the plant kingdom, some of which are used as anticancer …
ubiquitously distributed throughout the plant kingdom, some of which are used as anticancer …