International consensus statement on allergy and rhinology: Allergic rhinitis–2023

SK Wise, C Damask, LT Roland, C Ebert… - International forum of …, 2023 - Wiley Online Library
Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …

Epithelial cell dysfunction, a major driver of asthma development

IH Hei**k, VNS Kuchibhotla, MP Roffel, T Maes… - Allergy, 2020 - Wiley Online Library
Airway epithelial barrier dysfunction is frequently observed in asthma and may have
important implications. The physical barrier function of the airway epithelium is tightly …

Environmental influences on the epigenome: exposure-associated DNA methylation in human populations

EM Martin, RC Fry - Annual review of public health, 2018 - annualreviews.org
DNA methylation is the most well studied of the epigenetic regulators in relation to
environmental exposures. To date, numerous studies have detailed the manner by which …

Air pollution and DNA methylation: effects of exposure in humans

CF Rider, C Carlsten - Clinical epigenetics, 2019 - Springer
Air pollution exposure is estimated to contribute to approximately seven million early deaths
every year worldwide and more than 3% of disability-adjusted life years lost. Air pollution …

Epigenetics and allergy: from basic mechanisms to clinical applications

DP Potaczek, H Harb, S Michel, BA Alhamwe… - …, 2017 - Taylor & Francis
Allergic diseases are on the rise in the Western world and well-known allergy-protecting and-
driving factors such as microbial and dietary exposure, pollution and smoking mediate their …

Spotlight on microRNAs in allergy and asthma

J Weidner, S Bartel, A Kılıç, UM Zissler, H Renz… - Allergy, 2021 - Wiley Online Library
In past 10 years, microRNAs (miRNAs) have gained scientific attention due to their
importance in the pathophysiology of allergic diseases and their potential as biomarkers in …

Impact of weather and climate change with indoor and outdoor air quality in asthma: A Work Group Report of the AAAAI Environmental Exposure and Respiratory …

JA Poole, CS Barnes, JG Demain, JA Bernstein… - Journal of Allergy and …, 2019 - Elsevier
Weather and climate change are constant and ever-changing processes that affect allergy
and asthma. The purpose of this report is to provide information since the last climate …

Prenatal particulate air pollution and DNA methylation in newborns: an epigenome-wide meta-analysis

O Gruzieva, CJ Xu, P Yousefi, C Relton… - Environmental …, 2019 - ehp.niehs.nih.gov
Background: Prenatal exposure to air pollution has been associated with childhood
respiratory disease and other adverse outcomes. Epigenetics is a suggested link between …

Effects of long-term exposure to traffic-related air pollution on lung function in children

ES Schultz, AA Litonjua, E Melén - Current allergy and asthma reports, 2017 - Springer
Lung function in early life has been shown to be an important predictor for peak lung
function in adults and later decline. Reduced lung function per se is associated with …

Air pollution associated epigenetic modifications: Transgenerational inheritance and underlying molecular mechanisms

A Shukla, N Bunkar, R Kumar, A Bhargava… - Science of the total …, 2019 - Elsevier
Air pollution is one of the leading causes of deaths in Southeast Asian countries including
India. Exposure to air pollutants affects vital cellular mechanisms and is intimately linked …