Alternative pre-mRNA splicing is a tightly controlled process conducted by the spliceosome,
with the assistance of several regulators, resulting in the expression of different transcript …

Alternative splicing is a key process of multi-exonic gene expression during pre-mRNA
maturation. In this process, particular exons of a gene will be included within or excluded …

Matrin3 is an RNA‐and DNA‐binding nuclear matrix protein found to be associated with
neural and muscular degenerative diseases. A number of possible functions of Matrin3 have …

Nuclear retention of incompletely spliced or mature mRNAs emerges as a novel, previously
underappreciated layer of gene regulation, which enables the cell to rapidly respond to …

Alternative pre-mRNA splicing is key to proteome diversity; however, the biological roles of
alternative splicing (AS) in signaling pathways remain elusive. Here, we focus on TEA …

The dystrophin protein encoding DMD gene is the longest human gene. The 2.2 Mb long
human dystrophin transcript takes 16 hours to be transcribed and is co-transcriptionally …

The splicing factor Cwf15 is an essential component of the Prp19‐associated component of
the spliceosome and regulates intron splicing in several model species, including yeasts …

Alternative gene splicing, occurring ubiquitously in multicellular organisms can produce
several protein isoforms with putatively different functions. The enormously extended …

Background Microexons, exons that are≤ 30 nucleotides, are a highly conserved and
dynamically regulated set of cassette exons. They have key roles in nervous system …

RBM4 participates in cell differentiation by regulating tissue-specific alternative pre-mRNA
splicing. RBM4 also has been implicated in neurogenesis in the mouse embryonic brain …