Oxidative stress in the pathophysiology of type 2 diabetes and related complications: Current therapeutics strategies and future perspectives

JS Bhatti, A Sehrawat, J Mishra, IS Sidhu… - Free Radical Biology …, 2022 - Elsevier
Abstract Type 2 diabetes (T2DM) is a persistent metabolic disorder rising rapidly worldwide.
It is characterized by pancreatic insulin resistance and β-cell dysfunction. Hyperglycemia …

Quercetin: A flavonol with multifaceted therapeutic applications?

G D'Andrea - Fitoterapia, 2015 - Elsevier
Great interest is currently centered on the biologic activities of quercetin a polyphenol
belonging to the class of flavonoids, natural products well known for their beneficial effects …

Health effects of quercetin: from antioxidant to nutraceutical

AW Boots, GRMM Haenen, A Bast - European journal of pharmacology, 2008 - Elsevier
Quercetin, a member of the flavonoids family, is one of the most prominent dietary
antioxidants. It is ubiquitously present in foods including vegetables, fruit, tea and wine as …

The biological activities, chemical stability, metabolism and delivery systems of quercetin: A review

W Wang, C Sun, L Mao, P Ma, F Liu, J Yang… - Trends in food science & …, 2016 - Elsevier
Background Quercetin, one of the most well-known flavonoids, has been included in human
diet for a long history. The use of quercetin has been widely associated with a great number …

Bioactive compounds of edible fruits with their anti-aging properties: A comprehensive review to prolong human life

R Dhalaria, R Verma, D Kumar, S Puri, A Tapwal… - Antioxidants, 2020 - mdpi.com
Aging is a complicated biological process in which functional and structural alterations in a
living organism take place over time. Reactive oxygen species is one of the main factors …

Novel mechanisms of natural antioxidant compounds in biological systems: involvement of glutathione and glutathione-related enzymes

R Masella, R Di Benedetto, R Varì, C Filesi… - The Journal of nutritional …, 2005 - Elsevier
Polyphenols are wide variety of compounds that occur in fruits and vegetables, wine, tea,
extra virgin olive oil, chocolate and other cocoa products. Several polyphenols have been …

Quercetin‐loaded ceria nanocomposite potentiate dual‐directional immunoregulation via macrophage polarization against periodontal inflammation

Y Wang, C Li, Y Wan, M Qi, Q Chen, Y Sun, X Sun… - Small, 2021 - Wiley Online Library
Macrophage polarization toward M1 phenotype (pro‐inflammation) is closely associated
with the destructive phase of periodontal inflammation. Nanoceria is verified to inhibit M1 …

A minireview of quercetin: from its metabolism to possible mechanisms of its biological activities

HG Ulusoy, N Sanlier - Critical Reviews in Food Science and …, 2020 - Taylor & Francis
Quercetin, one of the most taken flavonoid with diet, belongs to the family of flavonols in
which kaempferol and myricetin are also found. Quercetin occurs as a glycoside (with linked …

[BOOK][B] Oxidation and antioxidants in organic chemistry and biology

ET Denisov, IB Afanas' ev - 2005 - taylorfrancis.com
Providing a comprehensive review of reactions of oxidation for different classes of organic
compounds and polymers, and biological processes mediated by free radicals, Oxidation …

The therapeutic effects and mechanisms of quercetin on metabolic diseases: pharmacological data and clinical evidence

H Yi, H Peng, X Wu, X Xu, T Kuang… - Oxidative medicine …, 2021 - Wiley Online Library
Metabolic diseases have become major public health issues worldwide. Searching for
effective drugs for treating metabolic diseases from natural compounds has attracted …