In search of a new paradigm for protective immunity to TB
Clinical trials of vaccines against Mycobacterium tuberculosis are well under way and
results are starting to come in. Some of these results are not so encouraging, as exemplified …
results are starting to come in. Some of these results are not so encouraging, as exemplified …
[HTML][HTML] Tuberculosis and HIV co-infection—focus on the Asia-Pacific region
Tuberculosis (TB) is the leading opportunistic disease and cause of death in patients with
HIV infection. In 2013 there were 1.1 million new TB/HIV co-infected cases globally …
HIV infection. In 2013 there were 1.1 million new TB/HIV co-infected cases globally …
CD271+ Bone Marrow Mesenchymal Stem Cells May Provide a Niche for Dormant Mycobacterium tuberculosis
Mycobacterium tuberculosis (Mtb) can persist in hostile intracellular microenvironments
evading immune cells and drug treatment. However, the protective cellular niches where …
evading immune cells and drug treatment. However, the protective cellular niches where …
[HTML][HTML] CD4+ T cells re-wire granuloma cellularity and regulatory networks to promote immunomodulation following Mtb reinfection
JD Bromley, SKC Ganchua, SK Nyquist, P Maiello… - Immunity, 2024 - cell.com
Immunological priming—in the context of either prior infection or vaccination—elicits
protective responses against subsequent Mycobacterium tuberculosis (Mtb) infection …
protective responses against subsequent Mycobacterium tuberculosis (Mtb) infection …
Smoking increases risk of recurrence after successful anti-tuberculosis treatment: a population-based study
YF Yen, MY Yen, YS Lin, YP Lin… - … of Tuberculosis and …, 2014 - ingentaconnect.com
OBJECTIVE: To investigate whether tobacco smoking increases the risk of tuberculosis (TB)
recurrence and identify factors associated with TB recurrence among adults who had …
recurrence and identify factors associated with TB recurrence among adults who had …
Tuberculosis recurrence after completion treatment in a European city: reinfection or relapse?
JP Millet, E Shaw, À Orcau, M Casals, JM Miró… - PloS one, 2013 - journals.plos.org
Background Tuberculosis (TB) recurrence can be due to reinfection or relapse. The
contribution of each to TB incidence and the factors associated with recurrence are not well …
contribution of each to TB incidence and the factors associated with recurrence are not well …
Reduced antituberculosis drug concentrations in HIV-infected patients who are men or have low weight: implications for international dosing guidelines
Reduced antituberculosis drug concentrations may contribute to unfavorable treatment
outcomes among HIV-infected patients with more advanced immune suppression, and few …
outcomes among HIV-infected patients with more advanced immune suppression, and few …
Recurrent pulmonary tuberculosis in China, 2005 to 2021
T Li, B Zhang, X Du, S Pei, Z Jia, Y Zhao - JAMA Network Open, 2024 - jamanetwork.com
Importance Despite posing a significant challenge to global tuberculosis (TB) elimination
efforts, recurrent TB remains understudied due to the challenges of long-term observation …
efforts, recurrent TB remains understudied due to the challenges of long-term observation …
Diabetes and risk of tuberculosis relapse: nationwide nested case-control study
PH Lee, HC Lin, ASE Huang, SH Wei, MS Lai, HH Lin - PloS one, 2014 - journals.plos.org
The aim of this study was to investigate the association between diabetes mellitus (DM) and
tuberculosis (TB) relapse using the nationwide TB registry in Taiwan. We conducted a case …
tuberculosis (TB) relapse using the nationwide TB registry in Taiwan. We conducted a case …
Associated factors for tuberculosis recurrence in Taiwan: a nationwide nested case-control study from 1998 to 2010
CL Hung, JY Chien, CY Ou - PloS one, 2015 - journals.plos.org
Background The contribution of human immunodeficiency virus (HIV) co-infection to
tuberculosis (TB) recurrence is well established worldwide. We conducted this study to …
tuberculosis (TB) recurrence is well established worldwide. We conducted this study to …