In search of a new paradigm for protective immunity to TB

C Nunes-Alves, MG Booty, SM Carpenter… - Nature Reviews …, 2014 - nature.com
Clinical trials of vaccines against Mycobacterium tuberculosis are well under way and
results are starting to come in. Some of these results are not so encouraging, as exemplified …

[HTML][HTML] Tuberculosis and HIV co-infection—focus on the Asia-Pacific region

QM Trinh, HL Nguyen, VN Nguyen, TVA Nguyen… - International Journal of …, 2015 - Elsevier
Tuberculosis (TB) is the leading opportunistic disease and cause of death in patients with
HIV infection. In 2013 there were 1.1 million new TB/HIV co-infected cases globally …

CD271+ Bone Marrow Mesenchymal Stem Cells May Provide a Niche for Dormant Mycobacterium tuberculosis

B Das, SS Kashino, I Pulu, D Kalita, V Swami… - Science translational …, 2013 - science.org
Mycobacterium tuberculosis (Mtb) can persist in hostile intracellular microenvironments
evading immune cells and drug treatment. However, the protective cellular niches where …

[HTML][HTML] CD4+ T cells re-wire granuloma cellularity and regulatory networks to promote immunomodulation following Mtb reinfection

JD Bromley, SKC Ganchua, SK Nyquist, P Maiello… - Immunity, 2024 - cell.com
Immunological priming—in the context of either prior infection or vaccination—elicits
protective responses against subsequent Mycobacterium tuberculosis (Mtb) infection …

Smoking increases risk of recurrence after successful anti-tuberculosis treatment: a population-based study

YF Yen, MY Yen, YS Lin, YP Lin… - … of Tuberculosis and …, 2014 - ingentaconnect.com
OBJECTIVE: To investigate whether tobacco smoking increases the risk of tuberculosis (TB)
recurrence and identify factors associated with TB recurrence among adults who had …

Tuberculosis recurrence after completion treatment in a European city: reinfection or relapse?

JP Millet, E Shaw, À Orcau, M Casals, JM Miró… - PloS one, 2013 - journals.plos.org
Background Tuberculosis (TB) recurrence can be due to reinfection or relapse. The
contribution of each to TB incidence and the factors associated with recurrence are not well …

Reduced antituberculosis drug concentrations in HIV-infected patients who are men or have low weight: implications for international dosing guidelines

H McIlleron, R Rustomjee, M Vahedi… - Antimicrobial agents …, 2012 - Am Soc Microbiol
Reduced antituberculosis drug concentrations may contribute to unfavorable treatment
outcomes among HIV-infected patients with more advanced immune suppression, and few …

Recurrent pulmonary tuberculosis in China, 2005 to 2021

T Li, B Zhang, X Du, S Pei, Z Jia, Y Zhao - JAMA Network Open, 2024 - jamanetwork.com
Importance Despite posing a significant challenge to global tuberculosis (TB) elimination
efforts, recurrent TB remains understudied due to the challenges of long-term observation …

Diabetes and risk of tuberculosis relapse: nationwide nested case-control study

PH Lee, HC Lin, ASE Huang, SH Wei, MS Lai, HH Lin - PloS one, 2014 - journals.plos.org
The aim of this study was to investigate the association between diabetes mellitus (DM) and
tuberculosis (TB) relapse using the nationwide TB registry in Taiwan. We conducted a case …

Associated factors for tuberculosis recurrence in Taiwan: a nationwide nested case-control study from 1998 to 2010

CL Hung, JY Chien, CY Ou - PloS one, 2015 - journals.plos.org
Background The contribution of human immunodeficiency virus (HIV) co-infection to
tuberculosis (TB) recurrence is well established worldwide. We conducted this study to …