The use of digital tools to measure physiological and behavioural variables of potential
relevance to mental health is a growing field sitting at the intersection between computer …

Monoamine oxidases (MAO-A and MAO-B) are mammalian flavoenzyme, which catalyze the
oxidative deamination of several neurotransmitters like norepinephrine, dopamine, tyramine …

Emerging evidence suggests that astrocyte loss is one of the most important pathological
features in the hippocampus of patients with major depressive disorder (MDD) and …

Major Depressive Disorder (MDD) is a leading cause of disability worldwide, creating a high
medical and socioeconomic burden. There is a growing interest in the biological …

Background Many depressed patients are not able to achieve or sustain symptom remission
despite serial treatment trials–often termed “treatment resistant depression”. A broader …

Background Subthreshold depression is highly prevalent in adolescence, but compared to
major depressive disorder, the clinical impact is under-researched. The aim of this review …

Nitrous oxide at 50% inhaled concentration has been shown to improve depressive
symptoms in patients with treatment-resistant major depression (TRMD). Whether a lower …

" The Practice of Electroconvulsive Therapy, Third Edition, provides a comprehensive yet
practical overview of the safe and effective use of ECT, with recommendations applicable …

Prevalence of mental disorders, including major depressive disorder (MDD), bipolar
disorder (BD) and schizophrenia (SZ) are increasing at alarming rates in our societies …

Brain-derived neurotrophic factor (BDNF) has been studied as a biomarker of major
depressive disorder (MDD). Besides diagnostic biomarkers, clinically useful biomarkers can …