Insect antimicrobial peptides: potential weapons to counteract the antibiotic resistance

MD Manniello, A Moretta, R Salvia, C Scieuzo… - Cellular and Molecular …, 2021 - Springer
Misuse and overuse of antibiotics have contributed in the last decades to a phenomenon
known as antibiotic resistance which is currently considered one of the principal threats to …

Klebsiella pneumoniae Biofilms and Their Role in Disease Pathogenesis

MES Guerra, G Destro, B Vieira, AS Lima… - Frontiers in cellular …, 2022 - frontiersin.org
The ability to form biofilms is a crucial virulence trait for several microorganisms, including
Klebsiella pneumoniae–a Gram-negative encapsulated bacterium often associated with …

Disulfide Bond-Containing Ajoene Analogues As Novel Quorum Sensing Inhibitors of Pseudomonas aeruginosa

J Fong, M Yuan, TH Jakobsen… - Journal of medicinal …, 2017 - ACS Publications
Since its discovery 22 years ago, the bacterial cell-to-cell communication system, termed
quorum sensing (QS), has shown potential as antipathogenic target. Previous studies …

Anti-biofilm and cytotoxicity activity of impregnated dressings with silver nanoparticles

JL Velázquez-Velázquez, A Santos-Flores… - Materials Science and …, 2015 - Elsevier
Infections arising from bacterial adhesion and colonization on chronic wounds are a
significant healthcare problem. Silver nanoparticles (AgNPs) impregnated in dressing have …

Polyethylene/silver-nanofiber composites: A material for antibacterial films

PA Zapata, M Larrea, L Tamayo, FM Rabagliati… - Materials Science and …, 2016 - Elsevier
Abstract Silver nanofibers (Ag-Nfbs)~ 80 nm in diameter were synthesized by hydrothermal
treatment. The nanofibers (3 and 5 wt%) were added in the initial feed together with the …

[HTML][HTML] Biofilm inhibition activity of compounds isolated from two Eunicea species collected at the Caribbean Sea

YM Díaz, GV Laverde, LR Gamba… - Revista Brasileira de …, 2015 - SciELO Brasil
Biofilm has a primary role in the pathogenesis of diseases and in the attachment of
multicellular organisms to a fouled surface. Because of that, the control of bacterial biofilms …

Design, synthesis and biological evaluation of 4-(alkyloxy)-6-methyl-2H-pyran-2-one derivatives as quorum sensing inhibitors

S Park, HS Kim, K Ok, YH Kim, HD Park… - Bioorganic & Medicinal …, 2015 - Elsevier
Novel pyrone-derived quorum sensing (QS) ligands to inhibit the binding of OdDHL to the
LasR of Pseudomonas aeruginosa were designed, synthesized and evaluated. Among the …

Design and synthesis of marine natural product-based 1H-indole-2, 3-dione scaffold as a new antifouling/antibacterial agent against fouling bacteria

MS Majik, C Rodrigues, S Mascarenhas, L D'Souza - Bioorganic chemistry, 2014 - Elsevier
Marine organisms such as seaweeds, sponges and corals protect their own surfaces from
fouling by their high anesthetic, repellant, and settlement inhibition properties. Within the …

The AhR ligand phthiocol and vitamin K analogs as Pseudomonas aeruginosa quorum sensing inhibitors

T Jia, D Liu, X Bi, M Li, Z Cai, J Fu, Z Liu, P Wu… - Frontiers in …, 2022 - frontiersin.org
The aryl hydrocarbon receptor (AhR) protein senses microbial-secreted metabolites to
trigger the host's innate immune system. The Pseudomonas quinolone signal (PQS) and …

Next generation quorum sensing inhibitors: Accounts on structure activity relationship studies and biological activities

MS Majik, UB Gawas, VK Mandrekar - Bioorganic & Medicinal Chemistry, 2020 - Elsevier
Bacterial resistance is a growing threat which represents major scourge throughout the
world. The suitable way to control the present critical situation of antimicrobial resistance …