Effects of dietary flavonoids on apoptotic pathways related to cancer chemoprevention

S Ramos - The Journal of nutritional biochemistry, 2007 - Elsevier
Epidemiological studies have described the beneficial effects of dietary polyphenols
(flavonoids) on the reduction of the risk of chronic diseases, including cancer. Moreover, it …

Enhancement of gastrointestinal absorption of quercetin by solid lipid nanoparticles

HL Li, XB Zhao, YK Ma, GX Zhai, LB Li… - Journal of Controlled …, 2009 - Elsevier
The aim of the present study is to design and characterize quercetin-loaded solid lipid
nanoparticles (QT-SLNs), clarify the absorption mechanism of QT-SLNs and to evaluate the …

Flavonoid Accumulation in Arabidopsis Repressed in Lignin Synthesis Affects Auxin Transport and Plant Growth

S Besseau, L Hoffmann, P Geoffroy, C Lapierre… - The Plant …, 2007 - academic.oup.com
In Arabidopsis thaliana, silencing of hydroxycinnamoyl-CoA shikimate/quinate
hydroxycinnamoyl transferase (HCT), a lignin biosynthetic gene, results in a strong reduction …

Bax/Bcl-2 cascade is regulated by the EGFR pathway: therapeutic targeting of non-small cell lung cancer

M Alam, S Alam, A Shamsi, M Adnan… - Frontiers in …, 2022 - frontiersin.org
Non-small cell lung carcinoma (NSCLC) comprises 80%–85% of lung cancer cases. EGFR
is involved in several cancer developments, including NSCLC. The EGFR pathway …

Beneficial roles of honey polyphenols against some human degenerative diseases: A review

MS Hossen, MY Ali, MHA Jahurul… - Pharmacological …, 2017 - Elsevier
Honey contains many active constituents and antioxidants such as polyphenols.
Polyphenols are phytochemicals, a generic term for the several thousand plant-based …

Review of the pharmacological effects of Vitis vinifera (Grape) and its bioactive compounds

M Nassiri‐Asl, H Hosseinzadeh - Phytotherapy Research: An …, 2009 - Wiley Online Library
Vitis vinifera, known as the grapevine, is native to southern Europe and Western Asia. Grape
seed and skin contain several active components including flavonoids, polyphenols …

[HTML][HTML] Emerging impact of quercetin in the treatment of prostate cancer

S Ghafouri-Fard, FA Shabestari, S Vaezi, A Abak… - Biomedicine & …, 2021 - Elsevier
Quercetin is a flavonoid agent detected in fruits and vegetables with anti-inflammatory,
antioxidant, and anticancer effects. This flavonoid can suppress cell cycle transition and …

[HTML][HTML] Quercetin induces apoptosis via caspase activation, regulation of Bcl-2, and inhibition of PI-3-kinase/Akt and ERK pathways in a human hepatoma cell line …

AB Granado-Serrano, MA Martiín, L Bravo, L Goya… - The Journal of …, 2006 - Elsevier
Dietary polyphenols have been associated with the reduced risk of chronic diseases such as
cancer, but the precise underlying mechanism of protection remains unclear. The aim of this …

Gold nanoparticles–conjugated quercetin induces apoptosis via inhibition of EGFR/PI3K/Akt–mediated pathway in breast cancer cell lines (MCF‐7 and MDA‐MB‐231)

S Balakrishnan, S Mukherjee, S Das… - Cell biochemistry …, 2017 - Wiley Online Library
Epidermal growth factor plays a major role in breast cancer cell proliferation, survival, and
metastasis. Quercetin, a bioactive flavonoid, is shown to exhibit anticarcinogenic effects …

Quercetin-induced apoptosis acts through mitochondrial-and caspase-3-dependent pathways in human breast cancer MDA-MB-231 cells

SY Chien, YC Wu, JG Chung, JS Yang… - Human & …, 2009 - journals.sagepub.com
There has been considerable evidence recently demonstrating the anti-tumour effects of
flavonols. Quercetin, an ubiquitous bioactive flavonol, inhibits cells proliferation, induces cell …