Acting now on dementia prevention, intervention, and care will vastly improve living and
dying for individuals with dementia and their families, and in doing so, will transform the …

Abstract Background and Purpose Mild Cognitive Impairment (MCI) is associated with a
greater risk of dementia for older adults. However, systematic reviews have shown that some …

In this narrative review, a theoretical framework on the crosstalk between physical exercise
and blood-brain barrier (BBB) permeability is presented. We discuss the influence of …

Over the past few decades, research on Alzheimer's disease (AD) has focused on
pathomechanisms linked to two of the major pathological hallmarks of extracellular …

The rate of age-associated cognitive decline varies considerably between individuals. It is
important, both on a societal and individual level, to investigate factors that underlie these …

Cognitive decline leading to dementia represents a global health burden. In the absence of
targeted pharmacotherapy, lifestyle approaches remain the best option for slowing the onset …

Aging is the major risk factor for neurodegenerative diseases, accelerated by excessive
calorie consumption and sedentary lifestyles. Bioenergetic challenges such as intermittent …

Background. Effects of Tai Chi (TC) on specific cognitive function and mechanisms by which
TC may improve cognition in older adults with amnestic mild cognitive impairment (a-MCI) …

Background Sedentary behaviour is associated with impaired cognition, whereas exercise
can acutely improve cognition. Objective We compared the effects of a morning bout of …

Background and Objectives The association between patterns of physical/mental activity
and dementia and how it is affected by disease susceptibility remains unknown. We aimed …