Pragnancy has commonly been viewed as a cooperative interaction between a mother and
her fetus. The effects of natural selection on genes expressed in fetuses, however, may be …

A profile characteristic of fuel economy in the mother during normal pregnancy has been
delineated. The evidence indicates that pregnancy changes the metabolism of every class of …

The incidence of gestational diabetes mellitus (GDM) has doubled over the last 6–8 years
and is paralleling the obesity epidemic. GDM carries longterm implications for the …

Pregnancy is associated with insulin resistance. We studied insulin binding and postbinding
function in isolated adipocytes from pregnant and nonpregnant rats. We also used a primary …

The placenta is essential for the success of therian mammalian reproduction. Intense
selective pressure has shaped changes in placental anatomy and function during …

BACKGROUND Metformin is an effective oral anti-hyperglycaemic drug used as first-line
medical treatment for type 2 diabetes. It improves systemic hyperglycaemia by reducing …

Assessment of the rates of disappearance of endogenous LH and HCG from serum
following complete surgical hypophysectomy and removal of the placenta was made. The …

Influences of estrogen and progesterone on the development of hyperinsulinemia and
augmented pancreatic islet insulin secretion during pregnancy were assessed in this study …

Reduced insulin sensitivity (insulin resistance) is a hallmark of normal physiology in late
pregnancy and also underlies gestational diabetes mellitus (GDM). We conducted …

This treatise is intended to provide a complete contemporary source of information on
fundamental and clinical aspects of endocrinology. It is published in three volumes; the first …