Insulin resistance and pancreatic β-cell dysfunction are major pathological mechanisms
implicated in the development and progression of type 2 diabetes (T2D). Beyond the …

Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …

Obesity is a critical risk factor for the development of type 2 diabetes (T2D), and its
prevalence is rising worldwide. White adipose tissue (WAT) has a crucial role in regulating …

Abstract Development of advanced modalities for detection of fat within the pancreas has
transformed understanding of the role of intra-pancreatic fat deposition (IPFD) in health and …

Waist circumference is a simple, inexpensive method to measure abdominal obesity. CT and
MRI are reference methods for measuring VAT. Further studies are needed to establish the …

Prevention of common diseases of the pancreas or interception of their progression is as
attractive in theory as it is elusive in practice. The fundamental challenge has been an …

Abstract Background & Aims Non‐alcoholic fatty liver disease (NAFLD) is a heterogeneous
disorder, but the factors that determine this heterogeneity remain poorly understood …

Aims/hypothesis Pancreatic fat accumulation may contribute to the development of beta cell
dysfunction. Exercise training improves whole-body insulin sensitivity, but its effects on …

Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest types of cancer. The
worldwide estimates of its incidence and mortality in the general population are eight cases …

Obesity, type 2 diabetes mellitus (T2 DM) and aging are associated with pancreatic cancer
risk, but the mechanisms of pancreatic cancer development caused by these factors are not …