Exosomes as a new frontier of cancer liquid biopsy

D Yu, Y Li, M Wang, J Gu, W Xu, H Cai, X Fang… - Molecular cancer, 2022 - Springer
Liquid biopsy, characterized by minimally invasive detection through biofluids such as
blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and …

Electrochemical biosensors for whole blood analysis: recent progress, challenges, and future perspectives

S Li, H Zhang, M Zhu, Z Kuang, X Li, F Xu… - Chemical …, 2023 - ACS Publications
Whole blood, as one of the most significant biological fluids, provides critical information for
health management and disease monitoring. Over the past 10 years, advances in …

A review of exosomal isolation methods: is size exclusion chromatography the best option?

K Sidhom, PO Obi, A Saleem - International journal of molecular sciences, 2020 - mdpi.com
Extracellular vesicles (EVs) are membranous vesicles secreted by both prokaryotic and
eukaryotic cells and play a vital role in intercellular communication. EVs are classified into …

Metal–organic framework-functionalized paper-based electrochemical biosensor for ultrasensitive exosome assay

X Liu, X Gao, L Yang, Y Zhao, F Li - Analytical chemistry, 2021 - ACS Publications
The exosome has emerged as a promising noninvasive biomarker for the early diagnosis of
cancer. Therefore, it is highly desirable to develop simple, inexpensive, and user-friendly …

Nanozyme-enabled analytical chemistry

S Li, Y Zhang, Q Wang, A Lin, H Wei - Analytical Chemistry, 2021 - ACS Publications
In 2007, landmark research recognized ferromagnetic nanoparticles (Fe3O4 NPs) as the
substitute of horseradish peroxidase (HRP) for their alike catalytic ability to oxidize signal …

Extracellular vesicles: A bright star of nanomedicine

P Wu, B Zhang, DKW Ocansey, W Xu, H Qian - Biomaterials, 2021 - Elsevier
Extracellular vesicles (EVs) have unique structural, compositional, and morphological
characteristics as well as predominant physiochemical stability and biocompatibility …

Gold nanozymes: from concept to biomedical applications

J Lou-Franco, B Das, C Elliott, C Cao - Nano-Micro Letters, 2021 - Springer
In recent years, gold nanoparticles have demonstrated excellent enzyme-mimicking
activities which resemble those of peroxidase, oxidase, catalase, superoxide dismutase or …

Precise Capture and Direct Quantification of Tumor Exosomes via a Highly Efficient Dual-Aptamer Recognition-Assisted Ratiometric Immobilization-Free …

L Yang, X Yin, B An, F Li - Analytical Chemistry, 2020 - ACS Publications
Tumor exosomes are promising biomarkers for early cancer diagnosis in a noninvasive
manner. However, precise capture and direct analysis of tumor-specific exosomes in …

Recent developments in isolating methods for exosomes

J Gao, A Li, J Hu, L Feng, L Liu, Z Shen - Frontiers in bioengineering …, 2023 - frontiersin.org
Exosomes are the smallest extracellular vesicles that can be released by practically all cell
types, and range in size from 30 nm to 150 nm. As the major marker of liquid biopsies …

Towards microfluidic-based exosome isolation and detection for tumor therapy

J Wang, P Ma, DH Kim, BF Liu, U Demirci - Nano Today, 2021 - Elsevier
Exosomes are a class of cell-secreted, nano-sized extracellular vesicles with a bilayer
membrane structure of 30–150 nm in diameter. Their discovery and application have …