Transient receptor potential (TRP) channels are sensors for a variety of cellular and
environmental signals. Mammals express a total of 28 different TRP channel proteins, which …

Calcium (Ca2+) is a unique mineral that serves as both a nutrient and a signal in all
eukaryotes. To maintain Ca2+ homeostasis for both nutrition and signaling purposes, the …

While modernization has dramatically increased lifespan, it has also witnessed the
increasing prevalence of diseases such as obesity, hypertension, and type 2 diabetes. Such …

TRPM7, a divalent cation-selective channel with kinase domains, has been widely reported
to potentially affect cancers. In this study, we conducted multiple bioinformatic analyses …

Nociception is an important physiological process that detects harmful signals and results in
pain perception. In this review, we discuss important experimental evidence involving some …

The common fruit fly, Drosophila melanogaster, is a well studied and highly tractable genetic
model organism for understanding molecular mechanisms of human diseases. Many basic …

The transient receptor potential superfamily of ion channels (TRP channels) is widely
recognized for the roles its members play in sensory nervous systems. However, the …

Abstract The TRP (Transient Receptor Potential) superfamily of cation channels is
remarkable in that it displays greater diversity in activation mechanisms and selectivities …

Abstract Purpose of Review Va** is gaining popularity in the USA, particularly among
teens and young adults. While e-cigs are commonly represented as safer alternatives to …

AN INTRODUCTION TO TRP CHANNELS Page 1 Annu. Rev. Physiol. 2006. 68:619–47 doi:
10.1146/annurev.physiol.68.040204.100431 Copyright cO 2006 by Annual Reviews. All rights …