Bitter taste-sensing type 2 receptors (TAS2Rs or T2Rs), belonging to the subgroup of family
A G-protein coupled receptors (GPCRs), are of crucial importance in the perception of …

Our sense of taste arises from the sensory information generated after compounds in the
oral cavity and oropharynx activate taste receptor cells situated on taste buds. This produces …

The tongue is a complex multifunctional organ that interacts and senses both interoceptively
and exteroceptively. Although it is easily visible to almost all of us, it is relatively …

Bitter taste perception plays vital roles in animal behavior and fitness. By signaling the
presence of toxins in foods, particularly noxious defense compounds found in plants, it …

We identified associations between cigarette-smoking and taste function in the US NHANES
2013–2014. Adults≥ 40 years (n= 2849, nearly half former or current smokers) rated whole …

In the last several decades, the genetic ability to taste the bitter compound, 6-n-
propyltiouracil (PROP) has attracted considerable attention as a model for understanding …

Clinical management of asthma and chronic obstructive pulmonary disease (COPD) has
primarily relied on the use of beta 2 adrenergic receptor agonists (bronchodilators) and …

The non-tasting form of the bitter taste receptor, TAS2R38, has been shown as a genetic risk
factor associated with the development of Parkinson's disease (PD). Specific taste receptors …

Bitter taste receptors play crucial roles in detecting bitter compounds not only in the oral
cavity, but also in extraoral tissues where they are involved in a variety of non‒tasting …

Background Neuroticism is associated with low emotional stability, and it is characterized by
a tendency to perceive ordinary situations as threatening and difficult to manage. This …