Growth factor delivery-based tissue engineering: general approaches and a review of recent developments

K Lee, EA Silva, DJ Mooney - Journal of the Royal …, 2011 - royalsocietypublishing.org
The identification and production of recombinant morphogens and growth factors that play
key roles in tissue regeneration have generated much enthusiasm and numerous clinical …

Natural polymers for gene delivery and tissue engineering

JM Dang, KW Leong - Advanced drug delivery reviews, 2006 - Elsevier
Although the field of gene delivery is dominated by viral vectors and synthetic polymeric or
lipid gene carriers, natural polymers offer distinct advantages and may help advance the …

Role of matrix metalloproteinases in delayed cortical responses after stroke

BQ Zhao, S Wang, HY Kim, H Storrie, BR Rosen… - Nature medicine, 2006 - nature.com
Matrix metalloproteinases (MMPs) are zinc-endopeptidases with multifactorial actions in
central nervous system (CNS) physiology and pathology. Accumulating data suggest that …

Biomaterial technology for tissue engineering applications

Y Tabata - Journal of the Royal Society interface, 2009 - royalsocietypublishing.org
Tissue engineering is a newly emerging biomedical technology and methodology to assist
and accelerate the regeneration and repairing of defective and damaged tissues based on …

Rational design of hydrogels for tissue engineering: impact of physical factors on cell behavior

F Brandl, F Sommer, A Goepferich - Biomaterials, 2007 - Elsevier
When designing suitable biomaterials for tissue-engineering applications, biological and
chemical parameters are frequently taken into account, while the equally important physical …

Controlled drug delivery in tissue engineering

M Biondi, F Ungaro, F Quaglia, PA Netti - Advanced drug delivery reviews, 2008 - Elsevier
The concept of tissue and cell guidance is rapidly evolving as more information regarding
the effect of the microenvironment on cellular function and tissue morphogenesis become …

Cell delivery mechanisms for tissue repair

DJ Mooney, H Vandenburgh - Cell stem cell, 2008 - cell.com
Many cell populations, derived from both adult tissues and embryonic stem cells, show
promise for the treatment of a variety of diseases. Although the major effort in stem cell …

[HTML][HTML] Spatiotemporal control of vascular endothelial growth factor delivery from injectable hydrogels enhances angiogenesis

EA Silva, DJ Mooney - Journal of Thrombosis and Haemostasis, 2007 - Elsevier
Therapeutic angiogenesis with vascular endothelial growth factor (VEGF) delivery may
provide a new approach for the treatment of ischemic diseases, but current strategies to …

Custom design of the cardiac microenvironment with biomaterials

ME Davis, PCH Hsieh, AJ Grodzinsky… - Circulation research, 2005 - Am Heart Assoc
Many strategies for repairing injured myocardium are under active investigation, with some
early encouraging results. These strategies include cell therapies, despite little evidence of …

Synthesis and evaluation of injectable, in situ crosslinkable synthetic extracellular matrices for tissue engineering

XZ Shu, S Ahmad, Y Liu… - Journal of biomedical …, 2006 - Wiley Online Library
Simple and effective biocompatible materials that mimic the natural extracellular matrix
(ECM) were developed for a variety of uses in regenerative medicine. These synthetic ECMs …