[HTML][HTML] Maternal soybean diet on prevention of obesity-related breast cancer through early-life gut microbiome and epigenetic regulation

M Chen, S Li, I Arora, N Yi, M Sharma, Z Li… - The Journal of nutritional …, 2022 - Elsevier
Overnutrition-induced obesity and metabolic dysregulation are considered major risk factors
contributing to breast cancer. The origin of both obesity and breast cancer can retrospect to …

Dietary supplementation of inulin contributes to the prevention of estrogen receptor-negative mammary cancer by alteration of gut microbial communities and …

H Wu, WJ Van Der Pol, LG Dubois, CD Morrow… - International Journal of …, 2023 - mdpi.com
Breast cancer (BC) is among the most frequently diagnosed malignant cancers in women in
the United States. Diet and nutrition supplementation are closely related to BC onset and …

Exploring the Complex Mechanisms of Isoflavones: From Cell Bioavailability, to Cell Dynamics and Breast Cancer

F Ferriere, N Aasi, G Flouriot… - Phytotherapy Research, 2024 - Wiley Online Library
In Western countries, the increase in the consumption of soy‐derived products raises the
population's exposure to isoflavones. These molecules, present in many foods, have …

[HTML][HTML] Paternal combined botanicals contribute to the prevention of estrogen receptor–negative mammary Cancer in transgenic mice

S Li, H Wu, M Chen, TO Tollefsbol - The Journal of Nutrition, 2023 - Elsevier
Background Parental nutritional interventions have considerably affected gametogenesis
and embryogenesis, leading to the differential susceptibility of offspring to chronic diseases …

Unleashing the potential of Genistein and its derivatives as effective therapeutic agents for breast cancer treatment

E Qaed, W Liu, M Almoiliqy, R Mohamed… - … Archives of Pharmacology, 2024 - Springer
Breast cancer remains one of the leading causes of cancer-related deaths among women
worldwide. Genistein (Gen), a phytoestrogen soy isoflavone, has emerged as a promising …

Pharmacodynamics and safety in relation to dose and response of plant flavonoids in treatment of cancers

CG Vazhappilly, S Alsawaf, S Mathew, NA Nasar… - …, 2024 - Springer
Despite the recent advancements in develo** bioactive nutraceuticals as anticancer
modalities, their pharmacodynamics, safety profiles, and tolerability remain elusive, limiting …

Epigenetics, Microbiota, and Breast Cancer: A Systematic Review

A Soldado-Gordillo, AI Álvarez-Mercado - Life, 2024 - mdpi.com
Breast cancer is the most frequently diagnosed cancer in women worldwide. According to
recent studies, alterations in the microbiota and epigenetic modulations are risk factors for …

Anticancer potential of different phytoconstituents against breast cancer: Is the hope for the new drug discovery

A Vikal, R Maurya, S Khare, S Bhargava, P Patel… - Pharmacological …, 2024 - Elsevier
This review explores the potential of phytoconstituents derived from plants as a novel and
effective strategy for treating breast cancer, a prevalent and life-threatening condition …

Decoding the transcriptome of muscular dystrophy due to Ptrf deficiency using single‐nucleus RNA sequencing

X Li, Z Zhong, R Zhang, J Zhang, Y Zhang… - The FASEB …, 2023 - Wiley Online Library
Lacking PTRF (polymerase I and transcript release factor), an essential caveolae
component, causes a secondary deficiency of caveolins resulting in muscular dystrophy …