The use of neuroimaging techniques in the early and differential diagnosis of dementia

L Chouliaras, JT O'Brien - Molecular Psychiatry, 2023 - nature.com
Dementia is a leading cause of disability and death worldwide. At present there is no
disease modifying treatment for any of the most common types of dementia such as …

Disentangling heterogeneity in Alzheimer's disease and related dementias using data-driven methods

M Habes, MJ Grothe, B Tunc, C McMillan, DA Wolk… - Biological …, 2020 - Elsevier
Brain aging is a complex process that includes atrophy, vascular injury, and a variety of age-
associated neurodegenerative pathologies, together determining an individual's course of …

[HTML][HTML] Can we really 'read'art to see the changing brain? A review and empirical assessment of clinical case reports and published artworks for systematic evidence …

M Pelowski, BTM Spee, J Arato, F Dörflinger… - Physics of life …, 2022 - Elsevier
The past three decades have seen multiple reports of people with neurodegenerative
disorders, or other forms of changes in their brains, who also show putative changes in how …

GBA1 Gene Mutations in α-Synucleinopathies—Molecular Mechanisms Underlying Pathology and Their Clinical Significance

Z Granek, J Barczuk, N Siwecka… - International Journal of …, 2023 - mdpi.com
α-Synucleinopathies comprise a group of neurodegenerative diseases characterized by
altered accumulation of a protein called α-synuclein inside neurons and glial cells. This …

Clinical and diagnostic implications of Alzheimer's disease copathology in Lewy body disease

L Barba, S Abu-Rumeileh, H Barthel, F Massa… - Brain, 2024 - academic.oup.com
Concomitant Alzheimer's disease (AD) pathology is a frequent event in the context of Lewy
body disease (LBD), occurring in approximately half of all cases. Evidence shows that LBD …

Neuroimaging in dementia

SL Risacher, LG Apostolova - CONTINUUM: Lifelong Learning in …, 2023 - journals.lww.com
OBJECTIVE Neurodegenerative diseases are significant health concerns with regard to
morbidity and social and economic hardship around the world. This review describes the …

Brain molecular connectivity in neurodegenerative diseases: recent advances and new perspectives using positron emission tomography

A Sala, D Perani - Frontiers in neuroscience, 2019 - frontiersin.org
Positron emission tomography (PET) represents a unique molecular tool to get in vivo
access to a wide spectrum of biological and neuropathological processes, of crucial …

[HTML][HTML] Diabetes and cognitive function: An evidence-based current perspective

MJ Sebastian, SKA Khan, JM Pappachan… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Several epidemiological studies have clearly identified diabetes mellitus (DM) as a major
risk factor for cognitive dysfunction, and it is going to be a major public health issue in the …

Robustly uncovering the heterogeneity of neurodegenerative disease by using data-driven subty** in neuroimaging: a review

P Chen, S Zhang, K Zhao, X Kang, T Rittman, Y Liu - Brain Research, 2024 - Elsevier
Neurodegenerative diseases are associated with heterogeneity in genetics, pathology, and
clinical manifestation. Understanding this heterogeneity is particularly relevant for clinical …

Mild cognitive impairment in dementia with Lewy bodies: an update and outlook

KA Jellinger - Journal of Neural Transmission, 2023 - Springer
Dementia with Lewy bodies (DLB), the second most common degenerative neurocognitive
disorder after Alzheimer disease (AD), is frequently preceded by a period of mild cognitive …