Protein homeostasis is a vital process for cell function and, therefore, disruption of the
molecular mechanisms involved in this process, such as autophagy, may contribute to …

Cyclodextrins are among the most remarkable macrocyclic molecules with significant
theoretical and practical impacts in chemistry and biology. Cyclodextrins belong to the family …

Effective therapy for Alzheimer's disease is a major challenge in the pharmaceutical
sciences. There are six FDA approved drugs (eg, donepezil, memantine) that show some …

Treatment of certain central nervous system disorders, including different types of cerebral
malignancies, is limited by traditional oral or systemic administrations of therapeutic drugs …

Cyclodextrins (CDs) are cyclic oligosaccharides; the most common CDs contain six, seven,
or eight glucose units called α-CDs, β-CDs, and γ-CDs, respectively. The use of CDs in …

The blood–brain barrier (BBB) limits the access of substances to the central nervous system
(CNS) which hinders the treatment of pathologies affecting the brain and the spinal cord …

Cyclodextrin (CD), a cyclic oligosaccharide, is a pharmaceutical additive that improves the
solubility of hydrophobic compounds. Recent research has focused on the potential active …

Cyclodextrins (CDs) have been used in many pharmaceutical formulations as their
constitution and inherent shape present advantages for drugs with poor aqueous solubility …

Abstract Objective Niemann–Pick type C (NPC) disease is a fatal, neurodegenerative,
lysosomal storage disorder characterized by intracellular accumulation of unesterified …

Cyclodextrin‐based polymers can be prepared starting from the naturally occurring
monomers following green and low‐cost procedures. They can be selectively derivatized …