Chronic inflammation and cytokines in the tumor microenvironment
Acute inflammation is a response to an alteration induced by a pathogen or a physical or
chemical insult, which functions to eliminate the source of the damage and restore …
chemical insult, which functions to eliminate the source of the damage and restore …
Radical causes of cancer
SP Hussain, LJ Hofseth, CC Harris - Nature Reviews Cancer, 2003 - nature.com
Free radicals are ubiquitous in our body and are generated by normal physiological
processes, including aerobic metabolism and inflammatory responses, to eliminate invading …
processes, including aerobic metabolism and inflammatory responses, to eliminate invading …
Intestinal inflammation and cancer
TA Ullman, SH Itzkowitz - Gastroenterology, 2011 - Elsevier
Patients with ulcerative colitis and Crohn's disease are at increased risk for develo**
colorectal cancer (CRC). Chronic inflammation is believed to promote carcinogenesis. The …
colorectal cancer (CRC). Chronic inflammation is believed to promote carcinogenesis. The …
Macrophages and cancer: from mechanisms to therapeutic implications
Infiltration by immune cells is a hallmark of most forms of malignancy. In this context, tumor-
associated macrophages (TAMs) represent key regulators of the complex interplay between …
associated macrophages (TAMs) represent key regulators of the complex interplay between …
Inflammation and cancer: an ancient link with novel potentials
S Perwez Hussain, CC Harris - International journal of cancer, 2007 - Wiley Online Library
Infection and chronic inflammation contribute to about 1 in 4 of all cancer cases. Mediators of
the inflammatory response, eg, cytokines, free radicals, prostaglandins and growth factors …
the inflammatory response, eg, cytokines, free radicals, prostaglandins and growth factors …
Inflammation, a key event in cancer development
H Lu, W Ouyang, C Huang - Molecular cancer research, 2006 - AACR
Several recent studies have identified nuclear factor-κB as a key modulator in driving
inflammation to cancers. Besides this transcription factor, essential in regulating …
inflammation to cancers. Besides this transcription factor, essential in regulating …
p53, cancer and the immune response
J Blagih, MD Buck, KH Vousden - Journal of cell science, 2020 - journals.biologists.com
The importance of cancer-cell-autonomous functions of the tumour suppressor p53
(encoded by TP53) has been established in many studies, but it is now clear that the p53 …
(encoded by TP53) has been established in many studies, but it is now clear that the p53 …
The chemical biology of nitric oxide: implications in cellular signaling
Nitric oxide (NO) has earned the reputation of being a signaling mediator with many diverse
and often opposing biological activities. The diversity in response to this simple diatomic …
and often opposing biological activities. The diversity in response to this simple diatomic …