Extracellular vesicles (eg, exosomes) carrying various biomolecules (eg, proteins, lipids,
and nucleic acids) have rapidly emerged as promising platforms for many biomedical …

Considering the high prevalence and the complex pharmacological management of immune-
mediated inflammatory diseases (IMIDs), the search for new therapeutic approaches for their …

The Human Mesenchymal Stem Cell (hMSC) secretome has pleiotropic effects
underpinning its therapeutic potential. hMSC serum-free conditioned media (SFCM) …

Cellular therapy aims to replace damaged resident cells by restoring cellular and molecular
environments suitable for tissue repair and regeneration. Among several candidates …

As double membrane‐encapsulated nanovesicles (30‐150 nm), exosomes (Exos) shuttle
between different cells to mediate intercellular communication and transport active cargoes …

Mesenchymal stem cells (MSCs), which exert regulatory effects on various immune cells,
have been a promising therapy for inflammatory bowel disease treatment. However, their …

Introduction Extracellular vesicles from mesenchymal stromal cells (MSC-EVs) have shown
promise in wound healing. Their use in diabetic wounds specifically, however, remains pre …

Obesity is characterized by low-grade inflammation, which is accompanied by increased
accumulation of immune cells in peripheral tissues including adipose tissue (AT), skeletal …

Background Longitudinal studies have verified the pivotal role of mesenchymal stem/stromal
cells (MSCs) in the bone marrow microenvironment for hematopoiesis and coordinate …

Background Local fistula injection of mesenchymal stromal/stem cells (MSC) is effective for
complex perianal Crohn's fistulas but is also expensive and requires specialised facilities for …