Alveolar lipids in pulmonary disease. A review

CW Agudelo, G Samaha, I Garcia-Arcos - Lipids in health and disease, 2020 - Springer
Lung lipid metabolism participates both in infant and adult pulmonary disease. The lung is
composed by multiple cell types with specialized functions and coordinately acting to meet …

Impact of lysosome status on extracellular vesicle content and release

E Eitan, C Suire, S Zhang, MP Mattson - Ageing research reviews, 2016 - Elsevier
Extracellular vesicles (EVs) are nanoscale size bubble-like membranous structures released
from cells. EVs contain RNA, lipids and proteins and are thought to serve various roles …

The pulmonary endothelium in acute respiratory distress syndrome: insights and therapeutic opportunities

FR Millar, C Summers, MJ Griffiths, MR Toshner… - Thorax, 2016 - thorax.bmj.com
The pulmonary endothelium is a dynamic, metabolically active layer of squamous
endothelial cells ideally placed to mediate key processes involved in lung homoeostasis …

Emerging role of extracellular vesicles as a senescence-associated secretory phenotype: Insights into the pathophysiology of lung diseases

T Kadota, Y Fujita, Y Yoshioka, J Araya… - Molecular aspects of …, 2018 - Elsevier
Aging is a major risk factor for the development of chronic lung diseases such as chronic
obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), and lung cancer …

[HTML][HTML] Lipid mediators regulate pulmonary fibrosis: potential mechanisms and signaling pathways

V Suryadevara, R Ramchandran, DW Kamp… - International journal of …, 2020 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease of unknown etiology
characterized by distorted distal lung architecture, inflammation, and fibrosis. The molecular …

Mitochondria in the spotlight of aging and idiopathic pulmonary fibrosis

AL Mora, M Bueno, M Rojas - The Journal of clinical investigation, 2017 - jci.org
Idiopathic pulmonary fibrosis (IPF) is a chronic age-related lung disease with high mortality
that is characterized by abnormal scarring of the lung parenchyma. There has been a recent …

The role of sphingosine-1-phosphate in autophagy and related disorders

S **ao, K Peng, C Li, Y Long, Q Yu - Cell Death Discovery, 2023 - nature.com
S1P, also referred to as sphingosine-1-phosphate, is a lipid molecule with bioactive
properties involved in numerous cellular processes such as cell growth, movement …

S100A12 as biomarker of disease severity and prognosis in patients with idiopathic pulmonary fibrosis

Y Li, Y He, S Chen, Q Wang, Y Yang, D Shen… - Frontiers in …, 2022 - frontiersin.org
Background Idiopathic pulmonary fibrosis (IPF) is one of interstitial lung diseases (ILDs) with
poor prognosis. S100 calcium binding protein A12 (S100A12) has been reported as a …

Microbes are associated with host innate immune response in idiopathic pulmonary fibrosis

Y Huang, SF Ma, MS Espindola, R Vij… - American journal of …, 2017 - atsjournals.org
Rationale: Differences in the lung microbial community influence idiopathic pulmonary
fibrosis (IPF) progression. Whether the lung microbiome influences IPF host defense …