Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …

Spinal cord injury (SCI) is an as yet untreatable neuropathology that causes severe
dysfunction and disability. Cell-based therapies hold neuroregenerative and neuroprotective …

Cervical spinal cord injury (SCI) leads to permanent impairment of arm and hand functions.
Here we conducted a prospective, single-arm, multicenter, open-label, non-significant risk …

Background How much scientific evidence is there to show that stem cell therapy is sufficient
in preclinical and clinical studies of spinal cord injury before it is translated into clinical …

Free radical formation and oxidative damage have been extensively investigated and
validated as important contributors to the pathophysiology of acute central nervous system …

Rehabilitative exercise in humans with spinal cord injury aims to engage residual neural
networks to improve functional recovery. We hypothesized that exercise combined with non …

Olfactory ensheathing cells show promise in preclinical animal models as a cell
transplantation therapy for repair of the injured spinal cord. This is a report of a clinical trial of …

An international panel reviewed the methodology for clinical trials of spinal cord injury (SCI),
and provided recommendations for the valid conduct of future trials. This is the second of …

There is an urgent need for both the scientific development and clinical validation of novel
therapies for acute spinal cord injury (SCI). The scientific development of novel therapies …

Stem cell therapy is a potential treatment for spinal cord injury (SCI), and a variety of different
stem cell types have been evaluated in animal models and humans with SCI. No consensus …