Developmental and epileptic encephalopathies (DEEs) are a heterogeneous group of
disorders characterized by early-onset, often severe epileptic seizures and EEG …

Synaptopathies are a class of neurodevelopmental disorders caused by modification in
genes coding for synaptic proteins. These proteins oversee the process of …

Preclinical applications of resting-state functional magnetic resonance imaging (rsfMRI) offer
the possibility to non-invasively probe whole-brain network dynamics and to investigate the …

Spontaneous brain activity as assessed with resting-state fMRI exhibits rich spatiotemporal
structure. However, the principles by which brain-wide patterns of spontaneous fMRI activity …

Fine-grained descriptions of brain connectivity are required to understand how neural
information is processed and relayed across spatial scales. Previous investigations of the …

Abstract Autism Spectrum Disorder (ASD) is characterized by substantial, yet highly
heterogeneous abnormalities in functional brain connectivity. However, the origin and …

Human genetic studies are rapidly identifying variants that increase risk for
neurodevelopmental disorders. However, it remains unclear how specific mutations impact …

Mutations in the synaptic scaffolding protein SHANK3 are a major cause of autism and are
associated with prominent intellectual and language deficits. However, the neural …

In rodent models of Autism Spectrum Disorders (ASD), the study of ultrasonic vocalizations
has provided the unique opportunity to evaluate social communication and interaction in …

Berberine, which is a potential antidepressant, exhibits definite efficiency in modulating the
gut microbiota. Depressive behaviors in mice induced using chronic unpredictable mild …