Challenges and directions in studying cell–cell communication by extracellular vesicles

G van Niel, DRF Carter, A Clayton… - … reviews Molecular cell …, 2022 - nature.com
Extracellular vesicles (EVs) are increasingly recognized as important mediators of
intercellular communication. They have important roles in numerous physiological and …

Therapeutically harnessing extracellular vesicles

L Cheng, AF Hill - Nature reviews Drug discovery, 2022 - nature.com
The field of extracellular vesicle (EV) research has developed rapidly over the last decade
from the study of fundamental biology to a subject of significant clinical relevance. The …

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

JA Welsh, DCI Goberdhan, L O'Driscoll… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

MicroRNA sequence codes for small extracellular vesicle release and cellular retention

R Garcia-Martin, G Wang, BB Brandão, TM Zanotto… - Nature, 2022 - nature.com
Exosomes and other small extracellular vesicles (sEVs) provide a unique mode of cell-to-
cell communication in which microRNAs (miRNAs) produced and released from one cell are …

Extracellular vesicle analysis

A Hendrix, L Lippens, C Pinheiro, C Théry… - Nature Reviews …, 2023 - nature.com
Cells release small, phospholipid membrane-enclosed particles, collectively referred to as
extracellular vesicles (EVs), into their surroundings to enable intercellular communication …

A brief history of nearly EV‐erything–The rise and rise of extracellular vesicles

Y Couch, EI Buzàs, D Di Vizio, YS Gho… - Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are small cargo‐bearing vesicles released by cells into the
extracellular space. The field of EVs has grown exponentially over the past two decades; this …

Extracellular vesicles as a next-generation drug delivery platform

IK Herrmann, MJA Wood, G Fuhrmann - Nature nanotechnology, 2021 - nature.com
Extracellular-vesicle-based cell-to-cell communication is conserved across all kingdoms of
life. There is compelling evidence that extracellular vesicles are involved in major (patho) …

Vesiclepedia 2024: an extracellular vesicles and extracellular particles repository

SV Chitti, S Gummadi, T Kang, S Shahi… - Nucleic Acids …, 2024 - academic.oup.com
Abstract Vesiclepedia (http://www. microvesicles. org) is a free web-based compendium of
DNA, RNA, proteins, lipids and metabolites that are detected or associated with extracellular …

A compendium of single extracellular vesicle flow cytometry

JA Welsh, GJA Arkesteijn, M Bremer… - Journal of …, 2023 - Wiley Online Library
Flow cytometry (FCM) offers a multiparametric technology capable of characterizing single
extracellular vesicles (EVs). However, most flow cytometers are designed to detect cells …

Formation of a protein corona on the surface of extracellular vesicles in blood plasma

EÁ Tóth, L Turiák, T Visnovitz, C Cserép… - Journal of …, 2021 - Wiley Online Library
In this study we tested whether a protein corona is formed around extracellular vesicles
(EVs) in blood plasma. We isolated medium‐sized nascent EVs of THP1 cells as well as of …