Neurobehavioral effects of environmental enrichment and drug abuse vulnerability: An updated review

SG Malone, JD Shaykin, DJ Stairs, MT Bardo - … Biochemistry and Behavior, 2022 - Elsevier
Environmental enrichment consisting of social peers and novel objects is known to alter
neurobiological functioning and have an influence on the behavioral effects of drugs of …

Interaction between stress and addiction: Contributions from Latin-American neuroscience

A Torres-Berrio, S Cuesta, S Lopez-Guzman… - Frontiers in …, 2018 - frontiersin.org
Drug addiction is a chronic neuropsychiatric disorder that escalates from an initial exposure
to drugs of abuse, such as cocaine, cannabis, or heroin, to compulsive drug-seeking and …

Environmental enrichment enhances conditioned place preference to ethanol via an oxytocinergic-dependent mechanism in male mice

M Rae, P Zanos, P Georgiou, P Chivers, A Bailey… - …, 2018 - Elsevier
Environmental conditions, such as stress and environmental enrichment (EE), influence
predisposition to alcohol use/abuse; however, the underlying mechanisms remain unknown …

Behavioral sensitization to ethanol: Neural basis and factors that influence its acquisition and expression

R Camarini, RM Pautassi - Brain research bulletin, 2016 - Elsevier
Ethanol-induced behavioral sensitization (EBS) was first described in 1980, approximately
10 years after the phenomenon was described for psychostimulants. Ethanol acts on γ …

Environmental enrichment reduces chronic psychosocial stress-induced anxiety and ethanol-related behaviors in mice

A Bahi - Progress in Neuro-Psychopharmacology and …, 2017 - Elsevier
Previous research from our laboratory has shown that exposure to chronic psychosocial
stress increased voluntary ethanol consumption and preference as well as acquisition of …

Environmental enrichment blunts ethanol consumption after restraint stress in C57BL/6 mice

P Marianno, KP Abrahao, R Camarini - PloS one, 2017 - journals.plos.org
Elevated alcohol intake after abstinence is a key feature of the addiction process. Some
studies have shown that environmental enrichment (EE) affects ethanol intake and other …

Epigenetic drugs and psychedelics as emerging therapies for alcohol use disorder: insights from preclinical studies

FF Hilal, J Jeanblanc, C Deschamps… - Journal of Neural …, 2024 - Springer
Alcohol use disorder (AUD) is a public health issue that affects millions of people worldwide
leading to physical, mental and socio-economic consequences. While current treatments for …

Post-weaning environmental enrichment, but not chronic maternal isolation, enhanced ethanol intake during periadolescence and early adulthood

LR Berardo, MC Fabio, RM Pautassi - Frontiers in behavioral …, 2016 - frontiersin.org
This study analyzed ethanol intake in male and female Wistar rats exposed to maternal
separation (MS) during infancy (postnatal days 1–21, PD1–21) and environmental …

Early exposure to environmental enrichment modulates the effects of prenatal ethanol exposure upon opioid gene expression and adolescent ethanol intake

A Wille-Bille, F Bellia, AMJ García… - …, 2020 - Elsevier
Prenatal ethanol exposure (PEE) promotes ethanol consumption in the adolescent offspring
accompanied by the transcriptional regulation of kappa opioid receptor (KOR) system …

Among Adolescents, BDNF and Pro‐BDNF Lasting Changes with Alcohol Use Are Stage Specific

MJ Miguez, D Bueno, L Espinoza, W Chan… - Neural …, 2020 - Wiley Online Library
Adolescent alcohol use demonstrates distinct developmental trajectories with dissimilar
times of onset and trajectories. Given the importance of brain‐derived neurotrophic factor …