Bacteriophages and their genomes

GF Hatfull, RW Hendrix - Current opinion in virology, 2011 - Elsevier
Bacteriophages occupy a unique position in biology, representing an absolute majority of all
organisms in the biosphere. Because their genomes are relatively small, elucidating the …

Mycobacteriophages: from petri dish to patient

GF Hatfull - PLoS pathogens, 2022 - journals.plos.org
Mycobacteriophages—bacteriophages infecting Mycobacterium hosts—contribute
substantially to our understanding of viral diversity and evolution, provide resources for …

[BOG][B] Discipline-based education research: Understanding and improving learning in undergraduate science and engineering

HA Schweingruber, NR Nielsen, SR Singer - 2012 - books.google.com
The National Science Foundation funded a synthesis study on the status, contributions, and
future direction of discipline-based education research (DBER) in physics, biological …

Ecology of inorganic sulfur auxiliary metabolism in widespread bacteriophages

K Kieft, Z Zhou, RE Anderson, A Buchan… - Nature …, 2021 - nature.com
Microbial sulfur metabolism contributes to biogeochemical cycling on global scales. Sulfur
metabolizing microbes are infected by phages that can encode auxiliary metabolic genes …

Bacteriophage evolution differs by host, lifestyle and genome

TN Mavrich, GF Hatfull - Nature Microbiology, 2017 - nature.com
Bacteriophages play key roles in microbial evolution 1, 2, marine nutrient cycling 3 and
human disease 4. Phages are genetically diverse, and their genome architectures are …

A broadly implementable research course in phage discovery and genomics for first-year undergraduate students

TC Jordan, SH Burnett, S Carson, SM Caruso, K Clase… - MBio, 2014 - journals.asm.org
Engaging large numbers of undergraduates in authentic scientific discovery is desirable but
difficult to achieve. We have developed a general model in which faculty and teaching …

PhiSpy: a novel algorithm for finding prophages in bacterial genomes that combines similarity- and composition-based strategies

S Akhter, RK Aziz, RA Edwards - Nucleic acids research, 2012 - academic.oup.com
Prophages are phages in lysogeny that are integrated into, and replicated as part of, the
host bacterial genome. These mobile elements can have tremendous impact on their …

Prophage-mediated defence against viral attack and viral counter-defence

RM Dedrick, D Jacobs-Sera, CAG Bustamante… - Nature …, 2017 - nature.com
Temperate phages are common, and prophages are abundant residents of sequenced
bacterial genomes. Mycobacteriophages are viruses that infect mycobacterial hosts …

Phamerator: a bioinformatic tool for comparative bacteriophage genomics

SG Cresawn, M Bogel, N Day, D Jacobs-Sera… - BMC …, 2011 - Springer
Background Bacteriophage genomes have mosaic architectures and are replete with small
open reading frames of unknown function, presenting challenges in their annotation …

Phage auxiliary metabolic genes and the redirection of cyanobacterial host carbon metabolism

LR Thompson, Q Zeng, L Kelly, KH Huang… - Proceedings of the …, 2011 - pnas.org
Cyanophages infecting the marine cyanobacteria Prochlorococcus and Synechococcus
encode and express genes for the photosynthetic light reactions. Sequenced cyanophage …