Plant benzoic acids (BAs) are building blocks or important structural elements for numerous
primary and specialized metabolites, including plant hormones, cofactors, defense …

The protein databases contain an exponentially growing number of sequences as a result of
the recent increase in ease and decrease in cost of genome sequencing. The rate of data …

Novel metabolites distinct from canonical pathways can be identified through the integration
of three cheminformatics tools: BinVestigate, which queries the BinBase gas …

Over the last two decades, the number of gene/protein sequences gleaned from sequencing
projects of individual genomes and environmental DNA has grown exponentially. Only a tiny …

Cryoelectron tomography directly visualizes heterogeneous macromolecular structures in
their native and complex cellular environments. However, existing computer-assisted …

A central challenge of the postgenomic era is to comprehensively characterize the cellular
role of the∼ 20,000 proteins encoded in the human genome. To systematically study protein …

Our understanding of metabolism is limited by a lack of knowledge about the functions of
many enzymes. Here, we develop a high-throughput mass spectrometry approach to …

Folates are essential cofactors for one-carbon transfer reactions and are needed in the diets
of humans and animals. Because plants are major sources of dietary folate, plant folate …

Cyanobacteria are key organisms in the global ecosystem, useful models for studying
metabolic and physiological processes conserved in photosynthetic organisms, and …

Metabolism is one of the best‐understood cellular processes whose network topology of
enzymatic reactions is determined by an organism's genome. The influence of genes on …