Iridoid glycosides are a class of chemical structures with various pharmacological activities
and have excellent research potential. However, the poor stability, water solubility, and oral …

Human Immunodeficiency Virus (HIV) is the viral agent of Acquired Immunodeficiency
Syndrome (AIDS), and at present, there is no effective vaccine against HIV. Reverse …

The capacity of different naphthoquinones to inhibit and eradicate Yersinia enterocolitica
biofilm was investigated and possible mechanisms of action were evaluated. Inhibition of …

Catalpol is expected to possess diverse pharmacological actions including anti-cancer, anti-
inflammatory and hypoglycemic properties. Matrix metalloproteinase-2 (MMP-2) is closely …

Aims of the study The ability of Yersinia enterocolitica strains to form biofilms and the
capacity of different alkaloids to inhibit biofilm formation were investigated. Methods and …

Iridoid glycoside, which belongs to the polyhydroxy compound, is a kind of active ingredient
of traditional Chinese medicine with a wide range of sources, and has many …

Catalpol is one of the most abundant naturally occurring iridoids. Catalpol appears to
possess many excellent biological and pharmacological activities as shown in recent …

Background: The discovery of new chemotherapeutic agents still remains a continuous goal
to achieve. DNA polymerases and topoisomerases act in nucleic acids metabolism …

Faithful replication of DNA molecules by DNA polymerases is essential for genome integrity
and correct transmission of genetic information in all living organisms. DNA polymerases …

Using a feasible method, we generated a small focused library of structurally related
alkenylcoumarins. These compounds were evaluated as potential antitumoral agents …