Microfluidics: Fluid physics at the nanoliter scale

TM Squires, SR Quake - Reviews of modern physics, 2005‏ - APS
Microfabricated integrated circuits revolutionized computation by vastly reducing the space,
labor, and time required for calculations. Microfluidic systems hold similar promise for the …

Optical trap**

KC Neuman, SM Block - Review of scientific instruments, 2004‏ - pubs.aip.org
Since their invention just over 20 years ago, optical traps have emerged as a powerful tool
with broad-reaching applications in biology and physics. Capabilities have evolved from …

Molecular computation of solutions to combinatorial problems

LM Adleman - science, 1994‏ - science.org
The tools of molecular biology were used to solve an instance of the directed Hamiltonian
path problem. A small graph was encoded in molecules of DNA, and the" operations" of the …

Nanometre diameter fibres of polymer, produced by electrospinning

DH Reneker, I Chun - Nanotechnology, 1996‏ - iopscience.iop.org
Electrospinning uses electrical forces to produce polymer fibres with nanometre-scale
diameters. Electrospinning occurs when the electrical forces at the surface of a polymer …

Optical trap** and manipulation of neutral particles using lasers

A Ashkin - Proceedings of the National Academy of Sciences, 1997‏ - pnas.org
The techniques of optical trap** and manipulation of neutral particles by lasers provide
unique means to control the dynamics of small particles. These new experimental methods …

Stretching DNA with optical tweezers

MD Wang, H Yin, R Landick, J Gelles, SM Block - Biophysical journal, 1997‏ - cell.com
Force-extension (Fx) relationships were measured for single molecules of DNA under a
variety of buffer conditions, using an optical trap** interferometer modified to incorporate …

Nobel Lecture: The manipulation of neutral particles

S Chu - Reviews of Modern Physics, 1998‏ - APS
The written version of my lecture is a personal account of the development of laser cooling
and trap**. Rather than give a balanced history of the field, I chose to present a personal …

Flow-induced elongation of von Willebrand factor precedes tension-dependent activation

H Fu, Y Jiang, D Yang, F Scheiflinger, WP Wong… - Nature …, 2017‏ - nature.com
Von Willebrand factor, an ultralarge concatemeric blood protein, must bind to platelet GPIbα
during bleeding to mediate hemostasis, but not in the normal circulation to avoid thrombosis …

Recent advances in optical tweezers

JR Moffitt, YR Chemla, SB Smith… - Annu. Rev …, 2008‏ - annualreviews.org
It has been over 20 years since the pioneering work of Arthur Ashkin, and in the intervening
years, the field of optical tweezers has grown tremendously. Optical tweezers are now being …

Multiphoton microscopy in life sciences

K König - Journal of microscopy, 2000‏ - Wiley Online Library
Near infrared (NIR) multiphoton microscopy is becoming a novel optical tool of choice for
fluorescence imaging with high spatial and temporal resolution, diagnostics, photochemistry …