Chitosan for biomedical applications, promising antidiabetic drug delivery system, and new diabetes mellitus treatment based on stem cell

SI Othman, AM Alturki, GM Abu-Taweel… - International Journal of …, 2021 - Elsevier
Since chitosan's excellent pharmacokinetic and chemical properties, it is an attractive and
promising carbohydrate biopolymer in biomedical applications. Chitosan's beneficial …

Synergistic effect of novel chitosan combined metformin drug on streptozotocin-induced diabetes mellitus rat

G Arun, R Rajaram, K Kaleshkumar, N Gayathri… - International journal of …, 2020 - Elsevier
Metformin is widely used as a frontline medicine of type-II diabetes. Frequent overdose side-
effects and their consequent adversative need to be reduced. The novel source of marine …

Antidiabetic effects and safety profile of chitosan delivery systems loaded with new xanthine-thiazolidine-4-one derivatives: in vivo studies

SM Constantin, FG Lupascu, M Apotrosoaei… - Journal of Drug Delivery …, 2020 - Elsevier
Based on important biological effects associated with xanthine and thiazolidine-4-one
moieties, especially hypoglycemic and antioxidant, new xanthine derivatives with …

Kinetics, Equilibrium, and Thermodynamics for Conjugation of Chitosan with Insulin-Mimetic [meso-Tetrakis(4-sulfonatophenyl)porphyrinato]oxovanadate(IV)(4−) in …

CK Shaha, B Sarker, SK Mahalanobish, MS Hossain… - ACS …, 2023 - ACS Publications
This study investigated the conjugation of chitosan with the insulin-mimetic [meso-tetrakis (4-
sulfonatophenyl) porphyrinato] oxovanadate (IV)(4−), VO (tpps), in an aqueous medium as a …

[PDF][PDF] Fenugreek seed and its active agent diosgenin treatment effects on different metabolic parameters in rats

A Badale, A Pallag, M Kozma, C Hegedus, D Kovacs… - Farmacia, 2019 - researchgate.net
In the present study we investigated the effects of chronic oral treatment with fenugreek
seeds (Trigonella foenum-graecum, TFG) and diosgenin (DG), one of its saponins, on diet …

[PDF][PDF] NOVEL TOPICAL CHITOSAN/HYDROXYPROPYLMETHYL-CELLULOSE-BASED HYDROGELS CONTAINING FLUCONAZOLE AND SUCROSE ESTERS …

ANA MUŢ, L Vlaia, G Coneac, I Olariu, V VLAIA… - Farmacia, 2018 - researchgate.net
The purpose of this work was to formulate, prepare and evaluate novel topical hydrogels for
the fluconazole delivery, containing biocompatible, biodegradable, non-toxic, non-irritating …

[PDF][PDF] Anatomical and functional organization of the muscular aponeurotic cervicofacial system

MM Scutariu, D Hînganu, G Macovei… - Romanian Journal of Oral …, 2018 - rjor.ro
Superficial muscular aponeurotic system (SMAS) is a musculoskeletal sheath extending
from the frontal muscle to the platysma and it acts as a" contraction amplifier of the facial …

Chitosan-based delivery systems loaded with glibenclamide and lipoic acid: Formulation, characterization, and kinetic release studies

LG Confederat, I Motrescu, MI Condurache… - Applied Sciences, 2020 - mdpi.com
Featured Application This article presents the development and characterization of new
chitosan based polymeric systems containing glibenclamide and lipoic acid for diabetes …

[PDF][PDF] Comparative study of oral antidiabetic therapy and insulin therapy on hepatic steatosis in patients with type 2 diabetes mellitus

A Hoza, C Moldovan, DM FĂRCAȘ, A Pallag… - …, 2018 - farmaciajournal.com
In type 2 diabetes mellitus (DM) patients, hepatic steatosis is present in a much higher
proportion than in healthy people. In this study, we have evaluated the presence of steatosis …

[PDF][PDF] Optimization and influence of some physico-chemical parameters on the synthesis of chitosan-tripolyphosphate nanoparticles

IM Vasincu, L Profire, M Apotrosoaei… - …, 2019 - farmaciajournal.com
In the past decades, the researchers have focused their attention on the synthesis of new
polymeric nanoparticles as drug delivery systems based on their small particle size and …