The role of PFC networks in cognitive control and executive function

V Menon, M D'Esposito - Neuropsychopharmacology, 2022 - nature.com
Abstract Systems neuroscience approaches with a focus on large-scale brain organization
and network analysis are advancing foundational knowledge of how cognitive control …

Advancing functional connectivity research from association to causation

AT Reid, DB Headley, RD Mill… - Nature …, 2019 - nature.com
Cognition and behavior emerge from brain network interactions, such that investigating
causal interactions should be central to the study of brain function. Approaches that …

Uncovering hidden brain state dynamics that regulate performance and decision-making during cognition

J Taghia, W Cai, S Ryali, J Kochalka, J Nicholas… - Nature …, 2018 - nature.com
Human cognition is influenced not only by external task demands but also latent mental
processes and brain states that change over time. Here, we use novel Bayesian switching …

Solving brain circuit function and dysfunction with computational modeling and optogenetic fMRI

JH Lee, Q Liu, E Dadgar-Kiani - Science, 2022 - science.org
Can we construct a model of brain function that enables an understanding of whole-brain
circuit mechanisms underlying neurological disease and use it to predict the outcome of …

Dynamic causal brain circuits during working memory and their functional controllability

W Cai, S Ryali, R Pasumarthy, V Talasila… - Nature …, 2021 - nature.com
Control processes associated with working memory play a central role in human cognition,
but their underlying dynamic brain circuit mechanisms are poorly understood. Here we use …

Optogenetic stimulation of anterior insular cortex neurons in male rats reveals causal mechanisms underlying suppression of the default mode network by the salience …

V Menon, D Cerri, B Lee, R Yuan, SH Lee… - Nature …, 2023 - nature.com
The salience network (SN) and default mode network (DMN) play a crucial role in cognitive
function. The SN, anchored in the anterior insular cortex (AI), has been hypothesized to …

Animal functional magnetic resonance imaging: trends and path toward standardization

F Mandino, DH Cerri, CM Garin, M Straathof… - Frontiers in …, 2020 - frontiersin.org
Animal whole-brain functional magnetic resonance imaging (fMRI) provides a non-invasive
window into brain activity. A collection of associated methods aims to replicate observations …

Distinct neurochemical influences on fMRI response polarity in the striatum

DH Cerri, DL Albaugh, LR Walton, B Katz… - Nature …, 2024 - nature.com
The striatum, known as the input nucleus of the basal ganglia, is extensively studied for its
diverse behavioral roles. However, the relationship between its neuronal and vascular …

Neuronal dynamics of the default mode network and anterior insular cortex: Intrinsic properties and modulation by salient stimuli

THH Chao, B Lee, LM Hsu, DH Cerri, WT Zhang… - Science …, 2023 - science.org
The default mode network (DMN) is critical for self-referential mental processes, and its
dysfunction is implicated in many neuropsychiatric disorders. However, the …

It's about time: Linking dynamical systems with human neuroimaging to understand the brain

YJ John, KS Sawyer, K Srinivasan, EJ Müller… - Network …, 2022 - direct.mit.edu
Most human neuroscience research to date has focused on statistical approaches that
describe stationary patterns of localized neural activity or blood flow. While these patterns …