Microfluidic cell sorting: a review of the advances in the separation of cells from debulking to rare cell isolation

CW Shields Iv, CD Reyes, GP López - Lab on a Chip, 2015 - pubs.rsc.org
Accurate and high throughput cell sorting is a critical enabling technology in molecular and
cellular biology, biotechnology, and medicine. While conventional methods can provide high …

Fundamentals and application of magnetic particles in cell isolation and enrichment: a review

BD Plouffe, SK Murthy, LH Lewis - Reports on Progress in …, 2014 - iopscience.iop.org
Magnetic sorting using magnetic beads has become a routine methodology for the
separation of key cell populations from biological suspensions. Due to the inherent ability of …

Cell separation using tilted-angle standing surface acoustic waves

X Ding, Z Peng, SCS Lin, M Geri, S Li, P Li… - Proceedings of the …, 2014 - pnas.org
Separation of cells is a critical process for studying cell properties, disease diagnostics, and
therapeutics. Cell sorting by acoustic waves offers a means to separate cells on the basis of …

Micro total analysis systems: fundamental advances and biological applications

CT Culbertson, TG Mickleburgh… - Analytical …, 2014 - ACS Publications
It has been more than 20 years since the first micro total analysis systems (μTAS) papers
were published. Initial reports of these devices, which are also commonly referred to as …

Microfluidic blood cell sorting: now and beyond

ZTF Yu, KM Aw Yong, J Fu - Small, 2014 - Wiley Online Library
Blood plays an important role in homeostatic regulation with each of its cellular components
having important therapeutic and diagnostic uses. Therefore, separation and sorting of …

Continuous-flow microfluidic blood cell sorting for unprocessed whole blood using surface-micromachined microfiltration membranes

X Li, W Chen, G Liu, W Lu, J Fu - Lab on a Chip, 2014 - pubs.rsc.org
White blood cells (WBCs) constitute about 0.1% of the blood cells, yet they play a critical role
in innate and adaptive immune responses against pathogenic infections, allergic conditions …

Antibody-free isolation of rare cancer cells from blood based on 3D lateral dielectrophoresis

IF Cheng, WL Huang, TY Chen, CW Liu, YD Lin… - Lab on a Chip, 2015 - pubs.rsc.org
We present an antibody-free approach for the high-purity and high-throughput
dielectrophoretic (DEP) isolation of circulating tumour cells (CTCs) from blood in a …

Blood linear viscoelasticity by small amplitude oscillatory flow

G Tomaiuolo, A Carciati, S Caserta, S Guido - Rheologica Acta, 2016 - Springer
Blood is a complex fluid with non-Newtonian characteristics and consists primarily of a
concentrated suspension of red blood cells (RBCs) characterized by high deformability and …

Rapid and label-free microfluidic neutrophil purification and phenoty** in diabetes mellitus

HW Hou, C Petchakup, HM Tay, ZY Tam, R Dalan… - Scientific reports, 2016 - nature.com
Advanced management of dysmetabolic syndromes such as diabetes will benefit from a
timely mechanistic insight enabling personalized medicine approaches. Herein, we present …

Inertial microfluidics combined with selective cell lysis for high throughput separation of nucleated cells from whole blood

H Ramachandraiah, HA Svahn, A Russom - RSC advances, 2017 - pubs.rsc.org
The ability to rapidly analyze and extract information from peripheral blood cells has the
potential of providing a wealth of new information about immune function and general health …