Clinical relevance of brain volume measures in multiple sclerosis

N De Stefano, L Airas, N Grigoriadis, HP Mattle… - CNS drugs, 2014 - Springer
Multiple sclerosis (MS) is a chronic disease with an inflammatory and neurodegenerative
pathology. Axonal loss and neurodegeneration occurs early in the disease course and may …

Characterization of brain volume changes in aging individuals with normal cognition using serial magnetic resonance imaging

S Fujita, S Mori, K Onda, S Hanaoka… - JAMA Network …, 2023 - jamanetwork.com
Importance Characterizing longitudinal patterns of regional brain volume changes in a
population with normal cognition at the individual level could improve understanding of the …

Sex differences in cognitive trajectories in clinically normal older adults.

AC McCarrey, Y An, MH Kitner-Triolo… - Psychology and …, 2016 - psycnet.apa.org
Age effects on cognitive functioning are well-documented, but effects of sex on trajectories of
cognitive aging are less clear. We examined cognitive ability across a variety of measures …

Large-scale coupling of prefrontal activity patterns as a mechanism for cognitive control in health and disease: evidence from rodent models

I Negrón-Oyarzo, T Dib, L Chacana-Véliz… - Frontiers in Neural …, 2024 - frontiersin.org
Cognitive control of behavior is crucial for well-being, as allows subject to adapt to changing
environments in a goal-directed way. Changes in cognitive control of behavior is observed …

Establishing pathological cut-offs of brain atrophy rates in multiple sclerosis

N De Stefano, ML Stromillo, A Giorgio… - Journal of Neurology …, 2016 - jnnp.bmj.com
Objective To assess whether it is feasible to establish specific cut-off values able to
discriminate 'physiological'or 'pathological'brain volume rates in patients with multiple …

Temporal changes in total and hippocampal brain volume and cognitive function in patients with chronic heart failure—the COGNITION. MATTERS-HF cohort study

A Frey, GA Homola, C Henneges… - European heart …, 2021 - academic.oup.com
Aims We quantified the concurring dynamics affecting total and hippocampal brain volume
and cognitive function in patients with chronic heart failure (HF) over a period of three years …

The impact of 6 and 12 months in space on human brain structure and intracranial fluid shifts

KE Hupfeld, HR McGregor, JK Lee… - Cerebral cortex …, 2020 - academic.oup.com
As plans develop for Mars missions, it is important to understand how long-duration
spaceflight impacts brain health. Here we report how 12-month (n= 2 astronauts) versus 6 …

Subty** of mild cognitive impairment using a deep learning model based on brain atrophy patterns

K Kwak, KS Giovanello, A Bozoki, M Styner… - Cell Reports …, 2021 - cell.com
Trajectories of cognitive decline vary considerably among individuals with mild cognitive
impairment (MCI). To address this heterogeneity, subty** approaches have been …

Superficial white matter across development, young adulthood, and aging: volume, thickness, and relationship with cortical features

KG Schilling, D Archer, F Rheault, I Lyu, Y Huo… - Brain Structure and …, 2023 - Springer
Superficial white matter (SWM) represents a significantly understudied part of the human
brain, despite comprising a large portion of brain volume and making up a majority of cortico …

Impact of amyloid and tau positivity on longitudinal brain atrophy in cognitively normal individuals

M Fujishima, Y Kawasaki, T Mitsuhashi… - Alzheimer's Research & …, 2024 - Springer
Background Individuals on the preclinical Alzheimer's continuum, particularly those with
both amyloid and tau positivity (A+ T+), display a rapid cognitive decline and elevated …