Endocrine-disrupting chemicals: implications for human health

LG Kahn, C Philippat, SF Nakayama… - The lancet Diabetes & …, 2020 - thelancet.com
Since reports published in 2015 and 2016 identified 15 probable exposure–outcome
associations, there has been an increase in studies in humans of exposure to endocrine …

Obesity II: establishing causal links between chemical exposures and obesity

JJ Heindel, S Howard, K Agay-Shay, JP Arrebola… - Biochemical …, 2022 - Elsevier
Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …

Perfluoroalkyl/polyfluoroalkyl substances: links to cardiovascular disease risk

JJ Schlezinger, N Gokce - Circulation research, 2024 - ahajournals.org
Conservative estimates by the World Health Organization suggest that at least a quarter of
global cardiovascular diseases are attributable to environmental exposures. Associations …

Polycystic ovary syndrome: an evolutionary adaptation to lifestyle and the environment

J Parker, C O'brien, J Hawrelak, FL Gersh - International Journal of …, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is increasingly recognized as a complex metabolic
disorder that manifests in genetically susceptible women following a range of negative …

[HTML][HTML] Exposure to perfluoroalkyl chemicals and cardiovascular disease: experimental and epidemiological evidence

A Meneguzzi, C Fava, M Castelli… - Frontiers in endocrinology, 2021 - frontiersin.org
Polyfluoro-and perfluoro–alkyl substances (PFAS) are organic chemicals extensively used
worldwide for industry and consumer products. Due to their chemical stability, PFAS …

Determinants of per-and polyfluoroalkyl substances (PFAS) in midlife women: evidence of racial/ethnic and geographic differences in PFAS exposure

SK Park, Q Peng, N Ding, B Mukherjee… - Environmental research, 2019 - Elsevier
Background Per-and poly-fluoroalkyl substances (PFAS) are public health concerns
because of widespread exposure through contaminated foods/drinking water. Although …

[HTML][HTML] Fetal–maternal exposure to endocrine disruptors: Correlation with diet intake and pregnancy outcomes

A Rolfo, AM Nuzzo, R De Amicis, L Moretti, S Bertoli… - Nutrients, 2020 - mdpi.com
Endocrine-disrupting chemicals (EDCs) are exogenous substances able to mimic or to
interfere with the endocrine system, thus altering key biological processes such as organ …

Comparative toxicometabolomics of perfluorooctanoic acid (PFOA) and next-generation perfluoroalkyl substances

KY Gebreab, MNH Eeza, T Bai, Z Zuberi, J Matysik… - Environmental …, 2020 - Elsevier
Owing to environmental health concerns, a number of per-and polyfluoroalkyl substances
(PFAS) have been phased-out, and increasingly replaced by various chemical analogs …

Exposure to per-and polyfluoroalkyl substance and metabolic syndrome: A nationally representative cross-sectional study from NHANES, 2003–2018

M Wu, Z Zhu, R Wan, J Xu - Environmental Pollution, 2024 - Elsevier
Per-and polyfluoroalkyl substances (PFAS) are widespread organic pollutants with
endocrine-disrupting effects on human health, but the association of PFAS exposure with …

[HTML][HTML] Per-and polyfluoroalkyl substances and blood lipid levels in pre-diabetic adults—longitudinal analysis of the diabetes prevention program outcomes study

PID Lin, A Cardenas, R Hauser, DR Gold… - Environment …, 2019 - Elsevier
Exposure to per-and polyfluoroalkyl substances (PFASs) may interfere with lipid regulation.
However, most previous studies were cross-sectional with the risk of reverse causation …