Choline is an essential nutrient, but is also formed by de novo synthesis. Choline and its
derivatives serve as components of structural lipoproteins, blood and membrane lipids, and …

Metabolomics, an omic science in systems biology, is the global quantitative assessment of
endogenous metabolites within a biological system. Either individually or grouped as a …

The CDP–choline pathway of phosphatidylcholine (PtdCho) biosynthesis was first described
more than 50years ago. Investigation of the CDP–choline pathway in yeast provides a basis …

Few studies have examined associations between plasma choline metabolites and risk of
colorectal cancer. Therefore, we investigated associations between plasma biomarkers of …

Following the impetus of early clinical and experimental investigations, in vivo and in vitro
MRS studies of tumours pointed in the eighties to the possible significance of signals arising …

Citicoline is the generic name of the pharmaceutical substance that chemically is cytidine-
5′-diphosphocholine (CDP-choline), which is identical to the natural intracellular precursor …

Research on the association between dietary adherence and cancer risk is limited,
particularly concerning overall cancer risk and its underlying mechanisms. Using the UK …

Complement is a central part of the immune system that has developed as a first defense
against non-self cells. Neoplastic transformation is accompanied by an increased capacity of …

Anatomical and physiological imaging using CT and MRI are playing a critical role in
patients' diagnosis, disease characterization and treatment planning. CT-and MRI-based …

There are several definitions of biomarkers. A biomarker is a characteristic that can be
objectively measured and evaluated as an indicator of a physiological as well as a …