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Deriving physiological information from PET images: from SUV to compartmental modelling
Positron emission tomography (PET) imaging has made it possible to detect the in vivo
concentration of positron-emitting compounds accurately and non-invasively. In order to …
concentration of positron-emitting compounds accurately and non-invasively. In order to …
Kinetic modeling of amyloid binding in humans using PET imaging and Pittsburgh Compound-B
A valid quantitative imaging method for the measurement of amyloid deposition in humans
could improve Alzheimer's disease (AD) diagnosis and antiamyloid therapy assessment …
could improve Alzheimer's disease (AD) diagnosis and antiamyloid therapy assessment …
Spectral analysis of dynamic PET studies: a review of 20 years of method developments and applications
In Positron Emission Tomography (PET), spectral analysis (SA) allows the quantification of
dynamic data by relating the radioactivity measured by the scanner in time to the underlying …
dynamic data by relating the radioactivity measured by the scanner in time to the underlying …
Kinetic Modeling without Accounting for the Vascular Component Impairs the Quantification of [11C]PBR28 Brain PET Data
The positron emission tomography radioligand [11C] PBR28 targets translocator protein (18
kDa)(TSPO) and is a potential marker of neuroinflammation.[11C] PBR28 binding is …
kDa)(TSPO) and is a potential marker of neuroinflammation.[11C] PBR28 binding is …
Kinetic modelling of [11C]PBR28 for 18 kDa translocator protein PET data: A validation study of vascular modelling in the brain using XBD173 and tissue analysis
The 18 kDa translocator protein (TSPO) is a marker of microglia activation in the central
nervous system and represents the main target of radiotracers for the in vivo quantification of …
nervous system and represents the main target of radiotracers for the in vivo quantification of …
GABAA receptor availability is not altered in adults with autism spectrum disorder or in mouse models
Preliminary studies have suggested that γ-aminobutyric acid type A (GABAA) receptors, and
potentially the GABAA α5 subtype, are deficient in autism spectrum disorder (ASD) …
potentially the GABAA α5 subtype, are deficient in autism spectrum disorder (ASD) …
Kinetic modeling of [18F]FDG in skeletal muscle by PET: a four-compartment five-rate-constant model
Various modeling strategies have been developed to convert regional [18F]
fluorodeoxyglucose ([18F] FDG) concentration measured by positron emission tomography …
fluorodeoxyglucose ([18F] FDG) concentration measured by positron emission tomography …
Generalization of endothelial modelling of TSPO PET imaging: considerations on tracer affinities
The 18 kDa translocator protein (TSPO) is a marker of microglia activation and the main
target of positron emission tomography (PET) ligands for neuroinflammation. Previous works …
target of positron emission tomography (PET) ligands for neuroinflammation. Previous works …
Validation of the semiquantitative static SUVR method for 18F-AV45 PET by pharmacokinetic modeling with an arterial input function
Increased brain uptake of 18F-AV45 visualized by PET is a key biomarker for Alzheimer
disease (AD). The SUV ratio (SUVR) is widely used for quantification, but is subject to …
disease (AD). The SUV ratio (SUVR) is widely used for quantification, but is subject to …
A Variational Bayesian inference method for parametric imaging of PET data
Abstract In dynamic Positron Emission Tomography (PET) studies, compartmental models
provide the richest information on the tracer kinetics of the tissue. Inverting such models at …
provide the richest information on the tracer kinetics of the tissue. Inverting such models at …