Sensing internal bodily signals, or interoception, is fundamental to maintain life. However,
interoception should not be viewed as an isolated domain, as it interacts with exteroception …

In a striking display of trans-kingdom symbiosis, gut bacteria cooperate with their animal
hosts to regulate the development and function of the immune, metabolic and nervous …

The gut-brain axis plays an important role in maintaining homeostasis. Many intrinsic and
extrinsic factors influence signaling along this axis, modulating the function of both the …

Increasing evidence indicates that the brain regulates peripheral immunity, yet whether and
how the brain represents the state of the immune system remains unclear. Here, we show …

The gastrointestinal tract plays a role in the development and treatment of metabolic
diseases. During a meal, the gut provides crucial information to the brain regarding …

Food is a powerful natural reinforcer that guides feeding decisions. The vagus nerve
conveys internal sensory information from the gut to the brain about nutritional value; …

Atherosclerotic plaques develop in the inner intimal layer of arteries and can cause heart
attacks and strokes. As plaques lack innervation, the effects of neuronal control on …

Interoception refers to the representation of the internal states of an organism, and includes
the processes by which it senses, interprets, integrates, and regulates signals from within …

Progress in understanding brain–viscera interoceptive signaling is hindered by a dearth of
implantable devices suitable for probing both brain and peripheral organ neurophysiology …

Emotions are fundamental to our experience and behavior, affecting and motivating all
aspects of our lives. Scientists of various disciplines have been fascinated by emotions for …