CD69: from activation marker to metabolic gatekeeper

D Cibrián, F Sánchez‐Madrid - European journal of …, 2017 - Wiley Online Library
CD69 is a membrane‐bound, type II C‐lectin receptor. It is a classical early marker of
lymphocyte activation due to its rapid appearance on the surface of the plasma membrane …

[HTML][HTML] The universe of galectin-binding partners and their functions in health and disease

MF Troncoso, MT Elola, AG Blidner, L Sarrias… - Journal of Biological …, 2023 - Elsevier
Galectins, a family of evolutionarily conserved glycan-binding proteins, play key roles in
diverse biological processes including tissue repair, adipogenesis, immune cell …

Galectin-1: a jack-of-all-trades in the resolution of acute and chronic inflammation

V Sundblad, LG Morosi, JR Geffner… - The Journal of …, 2017 - journals.aai.org
Regulatory signals provide negative input to immunological networks promoting resolution
of acute and chronic inflammation. Galectin-1 (Gal-1), a member of a family of evolutionarily …

The functional requirement for CD69 in establishment of resident memory CD8+ T cells varies with tissue location

DA Walsh, H Borges da Silva, LK Beura… - The Journal of …, 2019 - journals.aai.org
Recent studies have characterized populations of memory CD8+ T cells that do not
recirculate through the blood but are, instead, retained in nonlymphoid tissues. Such CD8+ …

CD69 expression on regulatory T cells protects from immune damage after myocardial infarction

R Blanco-Domínguez, H de la Fuente… - The Journal of clinical …, 2022 - jci.org
Increasing evidence has pointed to the important function of T cells in controlling immune
homeostasis and pathogenesis after myocardial infarction (MI), although the underlying …

Galectin-1: a traditionally immunosuppressive protein displays context-dependent capacities

X Yu, J Qian, L Ding, S Yin, L Zhou… - International Journal of …, 2023 - mdpi.com
Galectin–Carbohydrate interactions are indispensable to pathogen recognition and immune
response. Galectin-1, a ubiquitously expressed 14-kDa protein with an evolutionarily …

Mucosa-associated invariant T cells link intestinal immunity with antibacterial immune defects in alcoholic liver disease

A Riva, V Patel, A Kurioka, HC Jeffery, G Wright, S Tarff… - Gut, 2018 - gut.bmj.com
Background/aims Intestinal permeability with systemic distribution of bacterial products are
central in the immunopathogenesis of alcoholic liver disease (ALD), yet links with intestinal …

Galectins: emerging regulatory checkpoints linking tumor immunity and angiogenesis

SP Méndez-Huergo, AG Blidner… - Current opinion in …, 2017 - Elsevier
Highlights•Galectins engage a number of glycosylated immune checkpoint
receptors.•Galectins alter T-cell and NK-cell activation, signaling and survival.•Galectins …

Longitudinal single-cell profiling reveals molecular heterogeneity and tumor-immune evolution in refractory mantle cell lymphoma

S Zhang, VC Jiang, G Han, D Hao, J Lian, Y Liu… - Nature …, 2021 - nature.com
The mechanisms driving therapeutic resistance and poor outcomes of mantle cell lymphoma
(MCL) are incompletely understood. We characterize the cellular and molecular …

The roles of toll-like receptor 4, CD33, CD68, CD69, or CD147/EMMPRIN for monocyte activation by the DAMP S100A8/S100A9

A Möller, SL Jauch-Speer, S Gandhi, T Vogl… - Frontiers in …, 2023 - frontiersin.org
The S100A8/A9 heterocomplex is an abundant damage-associated molecular pattern and
mainly expressed by monocytes, inflammatory activated keratinocytes and neutrophilic …