CD69: from activation marker to metabolic gatekeeper
D Cibrián, F Sánchez‐Madrid - European journal of …, 2017 - Wiley Online Library
CD69 is a membrane‐bound, type II C‐lectin receptor. It is a classical early marker of
lymphocyte activation due to its rapid appearance on the surface of the plasma membrane …
lymphocyte activation due to its rapid appearance on the surface of the plasma membrane …
[HTML][HTML] The universe of galectin-binding partners and their functions in health and disease
MF Troncoso, MT Elola, AG Blidner, L Sarrias… - Journal of Biological …, 2023 - Elsevier
Galectins, a family of evolutionarily conserved glycan-binding proteins, play key roles in
diverse biological processes including tissue repair, adipogenesis, immune cell …
diverse biological processes including tissue repair, adipogenesis, immune cell …
Galectin-1: a jack-of-all-trades in the resolution of acute and chronic inflammation
V Sundblad, LG Morosi, JR Geffner… - The Journal of …, 2017 - journals.aai.org
Regulatory signals provide negative input to immunological networks promoting resolution
of acute and chronic inflammation. Galectin-1 (Gal-1), a member of a family of evolutionarily …
of acute and chronic inflammation. Galectin-1 (Gal-1), a member of a family of evolutionarily …
The functional requirement for CD69 in establishment of resident memory CD8+ T cells varies with tissue location
Recent studies have characterized populations of memory CD8+ T cells that do not
recirculate through the blood but are, instead, retained in nonlymphoid tissues. Such CD8+ …
recirculate through the blood but are, instead, retained in nonlymphoid tissues. Such CD8+ …
CD69 expression on regulatory T cells protects from immune damage after myocardial infarction
R Blanco-Domínguez, H de la Fuente… - The Journal of clinical …, 2022 - jci.org
Increasing evidence has pointed to the important function of T cells in controlling immune
homeostasis and pathogenesis after myocardial infarction (MI), although the underlying …
homeostasis and pathogenesis after myocardial infarction (MI), although the underlying …
Galectin-1: a traditionally immunosuppressive protein displays context-dependent capacities
X Yu, J Qian, L Ding, S Yin, L Zhou… - International Journal of …, 2023 - mdpi.com
Galectin–Carbohydrate interactions are indispensable to pathogen recognition and immune
response. Galectin-1, a ubiquitously expressed 14-kDa protein with an evolutionarily …
response. Galectin-1, a ubiquitously expressed 14-kDa protein with an evolutionarily …
Mucosa-associated invariant T cells link intestinal immunity with antibacterial immune defects in alcoholic liver disease
Background/aims Intestinal permeability with systemic distribution of bacterial products are
central in the immunopathogenesis of alcoholic liver disease (ALD), yet links with intestinal …
central in the immunopathogenesis of alcoholic liver disease (ALD), yet links with intestinal …
Galectins: emerging regulatory checkpoints linking tumor immunity and angiogenesis
SP Méndez-Huergo, AG Blidner… - Current opinion in …, 2017 - Elsevier
Highlights•Galectins engage a number of glycosylated immune checkpoint
receptors.•Galectins alter T-cell and NK-cell activation, signaling and survival.•Galectins …
receptors.•Galectins alter T-cell and NK-cell activation, signaling and survival.•Galectins …
Longitudinal single-cell profiling reveals molecular heterogeneity and tumor-immune evolution in refractory mantle cell lymphoma
The mechanisms driving therapeutic resistance and poor outcomes of mantle cell lymphoma
(MCL) are incompletely understood. We characterize the cellular and molecular …
(MCL) are incompletely understood. We characterize the cellular and molecular …
The roles of toll-like receptor 4, CD33, CD68, CD69, or CD147/EMMPRIN for monocyte activation by the DAMP S100A8/S100A9
A Möller, SL Jauch-Speer, S Gandhi, T Vogl… - Frontiers in …, 2023 - frontiersin.org
The S100A8/A9 heterocomplex is an abundant damage-associated molecular pattern and
mainly expressed by monocytes, inflammatory activated keratinocytes and neutrophilic …
mainly expressed by monocytes, inflammatory activated keratinocytes and neutrophilic …