The role of iron regulation in immunometabolism and immune-related disease
Immunometabolism explores how the intracellular metabolic pathways in immune cells can
regulate their function under different micro-environmental and (patho-)-physiological …
regulate their function under different micro-environmental and (patho-)-physiological …
Networking between helminths, microbes, and mammals
NL Harris - Cell host & microbe, 2023 - cell.com
Just as mammals have coevolved with the intestinal bacterial communities that are part of
the microbiota, intestinal helminths represent an important selective force on their …
the microbiota, intestinal helminths represent an important selective force on their …
Genome-wide screen identifies curli amyloid fibril as a bacterial component promoting host neurodegeneration
C Wang, CY Lau, F Ma… - Proceedings of the …, 2021 - National Acad Sciences
Growing evidence indicates that gut microbiota play a critical role in regulating the
progression of neurodegenerative diseases such as Parkinson's disease. The molecular …
progression of neurodegenerative diseases such as Parkinson's disease. The molecular …
Bacterial diets differentially alter lifespan and healthspan trajectories in C. elegans
Diet is one of the more variable aspects in life due to the variety of options that organisms
are exposed to in their natural habitats. In the laboratory, C. elegans are raised on bacterial …
are exposed to in their natural habitats. In the laboratory, C. elegans are raised on bacterial …
Iron status and physical performance in athletes
A Solberg, H Reikvam - Life, 2023 - mdpi.com
Iron is an important mineral in the body, essential for muscle function and oxygen transport.
Adequate levels of iron in the blood are necessary for athletes, as iron-deficiency anemia …
Adequate levels of iron in the blood are necessary for athletes, as iron-deficiency anemia …
Genome‐wide association and environmental suppression of the mortal germline phenotype of wild C. elegans
The animal germline lineage needs to be maintained along generations. However, some
Caenorhabditis elegans wild isolates display a mortal germline phenotype, leading to …
Caenorhabditis elegans wild isolates display a mortal germline phenotype, leading to …
Mechanisms of ferritinophagy and ferroptosis in diseases
S Li, P Huang, F Lai, T Zhang, J Guan, H Wan… - Molecular …, 2024 - Springer
The discovery of the role of autophagy, particularly the selective form like ferritinophagy, in
promoting cells to undergo ferroptosis has inspired us to investigate functional connections …
promoting cells to undergo ferroptosis has inspired us to investigate functional connections …
C. elegans as a model for inter-individual variation in metabolism
BW Fox, O Ponomarova, YU Lee, G Zhang, GE Giese… - Nature, 2022 - nature.com
Individuals can exhibit differences in metabolism that are caused by the interplay of genetic
background, nutritional input, microbiota and other environmental factors,,–. It is difficult to …
background, nutritional input, microbiota and other environmental factors,,–. It is difficult to …
A diet of oxidative stress–adapted bacteria improves stress resistance and lifespan in C. elegans via p38-MAPK
Organisms across taxa face stresses including variable temperature, redox imbalance, and
xenobiotics. Successfully responding to stress and restoring homeostasis are crucial for …
xenobiotics. Successfully responding to stress and restoring homeostasis are crucial for …
Gut microbial genetic variation modulates host lifespan, sleep, and motor performance
Y Li, S Xu, L Wang, H Shi, H Wang, Z Fang… - The ISME …, 2023 - academic.oup.com
Recent studies have shown that gut microorganisms can modulate host lifespan and
activities, including sleep quality and motor performance. However, the role of gut microbial …
activities, including sleep quality and motor performance. However, the role of gut microbial …