The failure of animal models to predict therapeutic responses in humans is a major problem
that also brings into question their use for basic research. Organ-on-a-chip (organ chip) …

Biomedical research is undergoing a paradigm shift towards approaches centred on human
disease models owing to the notoriously high failure rates of the current drug development …

Abstract Organs-on-chips (OoCs), also known as microphysiological systems or 'tissue
chips'(the terms are synonymous), have attracted substantial interest in recent years owing …

The pharmaceutical industry has been desperately searching for efficient drug discovery
methods. Organ-on-a-Chip, a cutting-edge technology that can emulate the physiological …

Organ-on-chip (OOC) systems are revolutionizing tissue engineering by providing dynamic
models of tissue structure, organ-level function, and disease phenotypes using human cells …

Microfluidic chip technology is an emerging tool in the field of biomedical application.
Microfluidic chip includes a set of groves or microchannels that are engraved on different …

Cancer is one of the leading causes of human death, despite enormous efforts to explore
cancer biology and develop anticancer therapies. The main challenges in cancer research …

The first microfluidic microphysiological systems (MPS) entered the academic scene more
than 15 years ago and were considered an enabling technology to human in vitro (patho) …

Vascularization of 3D models represents a major challenge of tissue engineering and a key
prerequisite for their clinical and industrial application. The use of prevascularized models …

Organoids and cells in organ‐on‐chip platforms replicate higher‐level anatomical,
physiological, or pathological states of tissues and organs. These technologies are widely …