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Adverse effects of tyrosine kinase inhibitors in cancer therapy: pathophysiology, mechanisms and clinical management
S Shyam Sunder, UC Sharma… - Signal transduction and …, 2023 - nature.com
Since their invention in the early 2000s, tyrosine kinase inhibitors (TKIs) have gained
prominence as the most effective pathway-directed anti-cancer agents. TKIs have shown …
prominence as the most effective pathway-directed anti-cancer agents. TKIs have shown …
2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: Developed by the Task Force for the diagnosis and treatment of acute and …
The aim of this ESC Guideline is to help health professionals manage people with heart
failure (HF) according to the best available evidence. Fortunately, we now have a wealth of …
failure (HF) according to the best available evidence. Fortunately, we now have a wealth of …
2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic …
AR Lyon, T López-Fernández, LS Couch… - European Heart …, 2022 - academic.oup.com
ESC Guidelines e341 (1) the specific situation of the patient. In this respect, it is specified
that, unless otherwise provided for by national regulations, offlabel use of medication should …
that, unless otherwise provided for by national regulations, offlabel use of medication should …
Role of cardiovascular imaging in cancer patients receiving cardiotoxic therapies: a position statement on behalf of the H eart F ailure A ssociation (HFA), the E …
J Čelutkienė, R Pudil… - European journal of …, 2020 - Wiley Online Library
Cardiovascular (CV) imaging is an important tool in baseline risk assessment and detection
of CV disease in oncology patients receiving cardiotoxic cancer therapies. This position …
of CV disease in oncology patients receiving cardiotoxic cancer therapies. This position …
Role of serum biomarkers in cancer patients receiving cardiotoxic cancer therapies: a position statement from the Cardio‐Oncology Study Group of the Heart Failure …
R Pudil, C Mueller, J Čelutkienė… - European journal of …, 2020 - Wiley Online Library
Serum biomarkers are an important tool in the baseline risk assessment and diagnosis of
cardiovascular disease in cancer patients receiving cardiotoxic cancer treatments. Increases …
cardiovascular disease in cancer patients receiving cardiotoxic cancer treatments. Increases …
Artificial intelligence-enabled prediction of chemotherapy-induced cardiotoxicity from baseline electrocardiograms
R Yagi, S Goto, Y Himeno, Y Katsumata… - Nature …, 2024 - nature.com
Anthracyclines can cause cancer therapy-related cardiac dysfunction (CTRCD) that
adversely affects prognosis. Despite guideline recommendations, only half of the patients …
adversely affects prognosis. Despite guideline recommendations, only half of the patients …
Cardiovascular Toxicity of Proteasome Inhibitors: Underlying Mechanisms and Management Strategies: JACC: CardioOncology State-of-the-Art Review
G Georgiopoulos, N Makris, A Laina, F Theodorakakou… - Cardio Oncology, 2023 - jacc.org
Proteasome inhibitors (PIs) are the backbone of combination treatments for patients with
multiple myeloma and AL amyloidosis, while also indicated in Waldenström's …
multiple myeloma and AL amyloidosis, while also indicated in Waldenström's …
Cardioprotection using strain-guided management of potentially cardiotoxic cancer therapy: 3-year results of the SUCCOUR trial
T Negishi, P Thavendiranathan, M Penicka… - Cardiovascular …, 2023 - jacc.org
Background Global longitudinal strain (GLS) can predict cancer therapeutics–related
cardiac dysfunction and guide initiation of cardioprotection (CPT). Objectives In this study …
cardiac dysfunction and guide initiation of cardioprotection (CPT). Objectives In this study …
Adverse cardiovascular and pulmonary events associated with chimeric antigen receptor T-cell therapy
Background Pivotal trials of chimeric antigen receptor T-cell (CAR-T) have identified
common toxicities but may have been underpowered to detect cardiovascular and …
common toxicities but may have been underpowered to detect cardiovascular and …
A circular RNA derived from the insulin receptor locus protects against doxorubicin-induced cardiotoxicity
D Lu, S Chatterjee, K **ao, I Riedel… - European heart …, 2022 - academic.oup.com
Aims Cardiotoxicity leading to heart failure (HF) is a growing problem in many cancer
survivors. As specific treatment strategies are not available, RNA discovery pipelines were …
survivors. As specific treatment strategies are not available, RNA discovery pipelines were …