Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies

BL Edlow, J Claassen, ND Schiff… - Nature Reviews Neurology, 2021 - nature.com
Substantial progress has been made over the past two decades in detecting, predicting and
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …

The human connectome project's neuroimaging approach

MF Glasser, SM Smith, DS Marcus… - Nature …, 2016 - nature.com
Noninvasive human neuroimaging has yielded many discoveries about the brain. Numerous
methodological advances have also occurred, though inertia has slowed their adoption. This …

Next-generation MRI scanner designed for ultra-high-resolution human brain imaging at 7 Tesla

DA Feinberg, AJS Beckett, AT Vu, J Stockmann… - Nature …, 2023 - nature.com
To increase granularity in human neuroimaging science, we designed and built a next-
generation 7 Tesla magnetic resonance imaging scanner to reach ultra-high resolution by …

Multimodal MRI reveals brainstem connections that sustain wakefulness in human consciousness

BL Edlow, M Olchanyi, HJ Freeman, J Li… - Science Translational …, 2024 - science.org
Consciousness is composed of arousal (ie, wakefulness) and awareness. Substantial
progress has been made in map** the cortical networks that underlie awareness in the …

[HTML][HTML] An integrated approach to correction for off-resonance effects and subject movement in diffusion MR imaging

JLR Andersson, SN Sotiropoulos - Neuroimage, 2016 - Elsevier
In this paper we describe a method for retrospective estimation and correction of eddy
current (EC)-induced distortions and subject movement in diffusion imaging. In addition a …

Population-averaged atlas of the macroscale human structural connectome and its network topology

FC Yeh, S Panesar, D Fernandes, A Meola, M Yoshino… - Neuroimage, 2018 - Elsevier
A comprehensive map of the structural connectome in the human brain has been a coveted
resource for understanding macroscopic brain networks. Here we report an expert-vetted …

7 Tesla MRI of the ex vivo human brain at 100 micron resolution

BL Edlow, A Mareyam, A Horn, JR Polimeni, T Witzel… - Scientific data, 2019 - nature.com
We present an ultra-high resolution MRI dataset of an ex vivo human brain specimen. The
brain specimen was donated by a 58-year-old woman who had no history of neurological …

[HTML][HTML] Advances in resting state fMRI acquisitions for functional connectomics

L Raimondo, J Heij, N Priovoulos, P Kundu, RF Leoni… - Neuroimage, 2021 - Elsevier
Resting state functional magnetic resonance imaging (rs-fMRI) is based on spontaneous
fluctuations in the blood oxygen level dependent (BOLD) signal, which occur simultaneously …

Discovering a reaction–diffusion model for Alzheimer's disease by combining PINNs with symbolic regression

Z Zhang, Z Zou, E Kuhl, GE Karniadakis - Computer Methods in Applied …, 2024 - Elsevier
Misfolded tau proteins play a critical role in the progression and pathology of Alzheimer's
disease. Recent studies suggest that the spatio-temporal pattern of misfolded tau follows a …

Clinical intravoxel incoherent motion and diffusion MR imaging: past, present, and future

M Iima, D Le Bihan - Radiology, 2016 - pubs.rsna.org
The concept of diffusion magnetic resonance (MR) imaging emerged in the mid-1980s,
together with the first images of water diffusion in the human brain, as a way to probe tissue …