The worldwide epidemic of obesity has brought considerable attention to research aimed at
understanding the biology of adipocytes (fat cells) and the events occurring in adipose …

Accumulating evidence indicates that obesity is closely associated with an increased risk of
metabolic diseases such as insulin resistance, type 2 diabetes, dyslipidemia and …

Obesity is characterized by increased storage of fatty acids in an expanded adipose tissue
mass and is closely associated with the development of insulin resistance in peripheral …

The breakthrough discoveries of leptin and adiponectin more than two decades ago led to a
widespread recognition of adipose tissue as an endocrine organ. Many more adipose tissue …

Testosterone is a key hormone in the pathology of metabolic diseases such as obesity. Low
testosterone levels are associated with increased fat mass (particularly central adiposity) …

Testosterone is a hormone that plays a key role in carbohydrate, fat and protein metabolism.
It has been known for some time that testosterone has a major influence on body fat …

Much evidence has accumulated in the literature over the last fifteen years that indicates
vitamin A has a role in metabolic disease prevention and causation. This literature proposes …

Obesity is one of the main risk factors for type 2 diabetes mellitus (T2DM). It is closely related
to metabolic disturbances in the adipose tissue that primarily functions as a fat reservoir. For …

Over the past decade and a half it has become increasingly clear that adipose tissue is a
much more complex organ than was initially considered and that its metabolic functions …

Obesity and type II diabetes are characterized by insulin resistance in peripheral tissues. A
high caloric intake combined with a sedentary lifestyle is the leading cause of these …